ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ NHIỄM NẤM DA TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ

Abstract

Background: Dermatophytosis (dermatophytes) is the most common superficial fungal infection caused by Trichophyton, Microsporum, and Epidermophyton species parasitizing keratinized tissues such as skin, hair, and nails. Although non-fatal, dermatophytosis significantly affects quality of life. The disease is characterized by high recurrence and diverse clinical manifestations, which lead to difficulties in diagnosis and treatment. Objectives: To investigate the clinical characteristics of patients with dermatophytosis at Can Tho University of Medicine and Pharmacy Hospital in 2024-2025. To evaluate treatment outcomes in patients with dermatophytosis at Can Tho University of Medicine and Pharmacy Hospital in 2024-2025. Materials and methods: A descriptive cross-sectional analytical study was conducted on 60 patients diagnosed with dermatophytosis who presented for examination and treatment at Can Tho University of Medicine and Pharmacy Hospital. Results: The mean age of patients was 34.6 ± 17.4 years, with males accounting for 60%. The majority were students. Most patients had disseminated lesions at multiple sites, most commonly on the head, face, and neck. Clinically, pruritus and erythema were the most frequent symptoms, and skin lesions were predominantly oval or round. After 2 weeks of treatment, symptoms such as pruritus, erythema, vesicles, and scaling showed significant improvement; by week 4, the cure rates of erythema and pruritus reached approximately 84.8-87%, while scaling and vesicles achieved 88.8-90%. The rate of non-response was very low and progressively decreased. Conclusion: The treatment regimen provided sustainable efficacy with significant improvement over time, and itraconazole, whether used alone or in combination, demonstrated high effectiveness in the management of dermatophytosis.