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Issue: No. 91 (2025)
Section: Article
DOI: 10.58490/ctump.2025i91.4145
Date Published: 25/09/2025
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Ha, T. L., Ha, T. K., & Pham, T. S. (2025). EVALUATION OF CARBAPENEM ANTIBIOTIC USE IN INPATIENT TREATMENT AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2024 - 2025. Cantho Journal of Medicine and Pharmacy, 91, 155-162. https://doi.org/10.58490/ctump.2025i91.4145

EVALUATION OF CARBAPENEM ANTIBIOTIC USE IN INPATIENT TREATMENT AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2024 - 2025

Thoai Lam Ha1, , Thoai Ky Ha2, Thanh Suol Pham2
1 S.I.S Can Tho International General Hospital
2 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Carbapenems are antibiotics reserved for patients with severe infections and are also the drugs of choice for aerobic Gram-negative bacilli producing extended-spectrum βlactamases (ESBLs). The rational use of carbapenems is therefore an urgent issue. Objective: To evaluate the utilization patterns and appropriateness of carbapenem use in inpatients at Can Tho University of Medicine and Pharmacy Hospital in 2024-2025. Materials and methods: A retrospective review of 190 medical records of patients prescribed carbapenems from January 2024 to March 2025 was conducted. Results: The overall rate of appropriate carbapenem use was 65.3%, including indication (89.5%), dosage (82.6%), infusion duration (99.5%), and combination therapy (86.8%). Conclusion: Strengthening adherence to prescribing guidelines and regular updates of the hospital’s antibiogram are essential to improve clinical outcomes and curb carbapenem resistance. 

Keywords

carbapenem, Gram-negative, rational antibiotic use

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