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PROGNOSTIC VALUE OF CHA2DS2-VASC SCORE FOR ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION AT CAN THO CENTRAL GENERAL HOSPITAL
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Abstract
Background: The CHA2DS2-VASc score has mainly been used to predict the risk of embolic stroke in patients with nonvalvular atrial fibrillation. There has been a lot of research in the world which proved that the CHA2DS2-VASc scoring system could be used for risk stratification in patients with acute coronary syndrome. Objective: To investigate the rate of major adverse cardiovascular events and the value of the CHA2DS2-VASc score in predicting cardiovascular events in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Materials and methods: Patients were diagnosed with acute coronary syndrome undergoing coronary angiography and percutaneous coronary intervention at Can Tho Central General Hospital. The method was a cross- sectional study with analysis. Results: During 6 months of follow-up after percutaneous coronary intervention, major adverse cardiovascular events occurred in 8.3% of patients. The area under the ROC curve for the CHA2DS2-VASc score in predicting major adverse cardiovascular events was 0.825 (p=0.001). A cut-off value of ≥4 had a sensitivity of 70% and a specificity of 80.9%. A Kaplan-Meier analysis of CHA2DS2-VASc scores of ≥4 showed a higher rate of adverse events as compared with scores of <4 (log-rank test, p<0.001). Conclusion: The CHA2DS2-VASc score is useful for the prediction of cardiovascular events in acute coronary syndrome patients undergoing percutaneous coronary intervention.
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Keywords
Acute coronary syndrome, cardiovascular events, CHA2DS2-VASc
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