RELATIONSHIP BETWEEN SARCOPENIA AND INSULIN RESISTANCE IN ELDERLY PATIENTS WITH TYPE 2 DIABETES MELLITUS
Main Article Content
Abstract
Background: Sarcopenia is an emerging complication of type 2 diabetes mellitus, increasing the risk of falls, fractures, disability, and mortality in the elderly. Insulin resistance contributes to muscle loss and is further aggravated by sarcopenia, forming a vicious pathological cycle. Therefore, the association between sarcopenia and insulin resistance should be clearly identified in clinical practice. Objectives: To determine the prevalence of sarcopenia and insulin resistance in elderly patients with type 2 diabetes mellitus, and to investigate the association between sarcopenia and insulin resistance. Materials and methods: A cross-sectional descriptive study was conducted on 59 patients aged 60 years and older with type 2 diabetes mellitus, who attended the University of Medicine and Pharmacy Hospital, Can Tho, from December 2023 to December 2024. Results: The prevalence of sarcopenia was 54.2%, and the prevalence of insulin resistance was 32.4%. Sarcopenia and reduced appendicular skeletal muscle mass were significantly associated with insulin resistance (p = 0.004). No significant associations were found between reduced handgrip strength, decreased gait speed, and insulin resistance. Conclusion: Elderly patients with sarcopenia have a higher risk of insulin resistance compared to those without sarcopenia. Elderly patients with reduced appendicular skeletal muscle mass also have a higher risk of insulin resistance compared to those without reduced muscle mass.
Keywords
Sarcopenia, insulin resistance, type 2 diabetes mellitus, reduced appendicular skeletal muscle mass, elderly
Article Details
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