CHARACTERISTICS OF INDICATORS FOR ASSESSING SARCOPENIA IN ELDERLY PATIENTS WITH TYPE 2 DIABETES

Van Trinh Nguyen1, Truong Khanh Duy Le1, Huynh Thai Tran1, Thien Thao Van1, Tra My Nguyen1, Thi Minh Trang Luong1, Hoang Tin Nguyen1, Phan Hai Sam Nguyen1, Kieu Anh Tho Pham1, Thai Thanh Tam Tran1,
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Type 2 diabetes mellitus is a chronic metabolic disease commonly observed in the elderly, contributing significantly to an increased risk of sarcopenia, which adversely affects mobility and quality of life. Parameters such as skeletal muscle index, handgrip strength, and gait speed are known to vary by age and sex. Aging and chronic inflammation associated with type 2 diabetes mellitus can accelerate the decline of these muscle-related indices. Objectives: To describe the characteristics of sarcopenia-related indices in elderly patients with type 2 diabetes mellitus. Materials and methods: A cross-sectional controlled study was conducted on patients aged 60 years and older who attended the Can Tho University of Medicine and Pharmacy Hospital from December 2023 to December 2024. Results: Diabetic patients with low skeletal muscle mass were older (p = 0.022), had lower body weight (p < 0.001), lower body mass index (p < 0.001), and smaller waist circumference (p = 0.038) than those with normal skeletal muscle mass. Male patients showed significantly higher skeletal muscle mass, handgrip strength, and walking speed compared to female patients (p < 0.05). Patients aged 70 years and older exhibited significantly lower walking speed than those under 70 years of age (p = 0.001). Walking speed was also significantly lower among female patients (p =0.040) and among diabetic patients under 70 years of age (p = 0.025) compared to nondiabetic counterparts. Conclusion: Elderly patients with type 2 diabetes mellitus, reductions in skeletal muscle index, handgrip strength, and gait speed are associated with age, sex, and anthropometric characteristics. 

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References

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