NGHIÊN CỨU SỰ BIẾN ĐỔI NỒNG ĐỘ VÀ VAI TRÒ CỦA TROPONIN T SIÊU NHẠY TRONG TIÊN LƯỢNG BIẾN CỐ RỐI LOẠN NHỊP TIM Ở BỆNH NHÂN SAU PHẪU THUẬT VAN TIM TẠI BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG CẦN THƠ NĂM 2021-2022

Abstract

Background: In heart valve surgery to treat valve disease, every attempt is made to protect the myocardium, but myocardial damage is inevitable. The myocardial damage will increase high-sensitivity troponin T (hs-TnT) in the postoperative period and as a biomarker for the development of arrhythmia after heart valve surgery. Objective: Study variations and the prognostic role of hs-TnT for the development of arrhythmia after heart valve surgery at the cardiac surgery department, Can Tho central general hospital 2021-2022. Materials and methods: A cross-sectional descriptive study with analysis was carried out on 37 heart valve disease patients who indicated and had heart valve surgery. Recorded arrhythmia development by prolonged electrocardiogram monitoring. Results: After heart valve surgery, hs-TnT levels were highest at 4 hours after aortic clamp removal with an average value of 1.710±1.254ng/mL, and the rate of arrhythmia was 29.7% (11/37 patients). There was a positive correlation between hs-TnT levels at 4 hours after aortic clamp removal and arrhythmia development, the correct prediction rate was 81.1% (r=1,474, CI 95%: 1.637-11.647, p<0.01), the area under the ROC curve of hs-TnT levels for arrhythmia development was 87.1%, p<0.001 (the cut-off point of hsTnT levels for arrhythmia development was 2.650ng/mL with a sensitivity of 72.7% and a specificity of 88.5%). Conclusion: In patients after heart valve surgery, hs-TnT levels were highest at 4 hours after aortic clamp removal and was a positive correlation with arrhythmia development, hs-TnT levels ≥2.650ng/L were independently predictive of arrhythmia development.