KHẢO SÁT ĐẶC ĐIỂM LÂM SÀNG, ẢNH HƯỞNG CHẤT LƯỢNG CUỘC SỐNG VÀ KẾT QUẢ ĐIỀU TRỊ ĐAU DO ZONA BẰNG GABAPENTIN KẾT HỢP LASER HE-NE TẠI BỆNH VIỆN DA LIỄU CẦN THƠ NĂM 2024-2025

Abstract

Background: Herpes zoster results from the reactivation of the varicella-zoster virus, which persists in a dormant state within the sensory ganglia following primary infection. Clinically, it presents as a painful, unilateral vesicular eruption confined to a single dermatome. The acute phase of the disease is often associated with significant pain, which can markedly impair the patient's quality of life. Currently, many methods are applied to treat herpes zoster including gabapentin and He-Ne laser. However, the effectiveness of their combination in relieving zoster-associated pain remains unclear. Objectives: To characterize the clinical presentation of herpes zoster, assess its impact on quality of life, and evaluate the effectiveness of pain management using a combined regimen of gabapentin and He-Ne laser therapy. Materials and methods: A descriptive crosssectional study was conducted on a cohort of 33 patients diagnosed with herpes zoster at Can Tho Hospital of Dermato-Venereology between July 2024 and February 2025. Results: Most patients came to the clinic quite late with an average illness duration of 4.55 ± 2.12 days. The most common primary lesions  were erythematous plaques (100%) and vesicles (100%). The head-face-neck was the most frequently affected area (42.4%) and lesions were usually located on the right side (57.6%). Patients with severe pain were the majority (60.6%) and the average DLQI score was 19.52 ± 4.52. At the end of treatment, 51.5% of patients had good improvement, and 39.4% of patients had moderate response. The main adverse effects were drowsiness and dizziness (15.1% and 12.1%, respectively). Conclusion: The combined use of gabapentin and helium-neon laser therapy represents a safe and efficacious approach for managing herpes zoster.