Article Sidebar

PDF
Issue: No. 91 (2025)
Section: Article
DOI: 10.58490/ctump.2025i91.3838
Date Published: 25/09/2025
Views 0
Downloads 0
How to Cite
Nguyen, T. H. O., Truong, N. Y., Truong, T. D., Nguyen, T. T. D., Nguyen, M. K., Le, V. M., & Le, N. T. (2025). SOME GENDER DIFFERENCES IN ISCHEMIC STROKE PATIENTS AT CAN THO GENERAL HOSPITAL. Cantho Journal of Medicine and Pharmacy, 91, 45-52. https://doi.org/10.58490/ctump.2025i91.3838

SOME GENDER DIFFERENCES IN ISCHEMIC STROKE PATIENTS AT CAN THO GENERAL HOSPITAL

Thi Hoang Oanh Nguyen1, Nhu Y Truong1, Tan Dat Truong1, Thi Thuy Duong Nguyen1, Minh Khoi Nguyen1, Van Minh Le1, Nhut Tan Le1,
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Patients with ischemic stroke exhibit clinical and treatment outcome differences between genders. While studies on ischemic stroke have been conducted in Can Tho, they have not focused on clarifying these gender-based differences. Objectives: To describe the differences in clinical characteristics and outcomes of ischemic stroke patients between males and females. Materials and methods: A cross-sectional study was conducted on 124 ischemic stroke patients at Can Tho General Hospital from July 2024 to December 2024. Results: Among the 124 patients (76 males, 48 females, average age 67±10 years), males had higher risk factors such as hypertension, smoking, and alcohol use (p<0.05). Conversely, females had higher rates of diabetes, dyslipidemia, and coronary artery disease (p<0.05). According to the TOAST classification, females had a higher proportion of small vessel disease-related strokes (p=0.033). After 3 months followup, men had more functional dependence mRS>2 than women, however, there was no statistical difference (p=0.712). Conclusions: Gender differences exist in risk factors, TOAST classification subtypes, and there is no difference in outcomes between the two genders three months after a stroke. 

Keywords

ischemic stroke, gender, different

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

References

1. Ashour W, AbdElghaffar AS, et al. Sex Differences in Clinical Presentation, Severity and Outcome in patients with acute ischemic stroke; a prospective cohort study. Zagazig University Medical Journal. 2021. 27(5), 973-83, https://doi.org/10.1212/WNL.0000000000007533.
2. Poggesi A, Insalata G, Papi G, Inzitari D, Monroe B, Simoni D, et al. Gender differences in post-stroke functional outcome at discharge from an intensive rehabilitation hospital. Eur J Neurol. 2021.28(6),1873-1881, https://doi:10.1111/ene.14769.
3. Jan Hendrik Schaefer, FO Bohmann, F Lieschke, B Misselwitz et al. Divergence and Convergence of Sex‐Specific Time Trends in Ischemic Stroke: 10‐Year Analysis of a StateWide Registry in Germany. Journal of the American Heart Association. 2022. 11(20), e027130, https://doi.org/10.1161/JAHA.122.027130.
4. Stuart-Shor EM, Wellenius GA, et al. Gender differences in presenting and prodromal stroke symptoms. Stroke. 2009. 40(4),1121-6, https://doi.org/10.1161/STROKEAHA.108.543371.
5. Peters SA, et al. Smoking as a risk factor for stroke in women compared with men: A systematic review and meta-analysis of 81 cohorts, including 3 980 359 individuals and 42 401 strokes. Stroke. 2013. 44(10), 2821-8, https://doi.org/10.1161/STROKEAHA.113.002342.
6. Ahangar AA, Saadat P, Heidari B, Taheri ST, Alijanpour S. Sex difference in types and distribution of risk factors in ischemic and hemorrhagic stroke. International journal of stroke. 2018. 13(1), 83-6, https://doi.org/10.1177/1747493017724626.
7. Maeda K, Toyoda K, Japan Standard Stroke Registry Study Group. Effects of sex difference on clinical features of acute ischemic stroke in Japan. Journal of Stroke and Cerebrovascular Diseases. 2013. 22(7),1070-5, https://doi.org/10.1016/j.jstrokecerebrovasdis.2012.07.006.
8. Ong CT, Wong YS, et al. Sex-related differences in the risk factors for in-hospital mortality and outcomes of ischemic stroke patients in rural areas of Taiwan. PLoS One. 2017 . 12(9), e0185361, https://doi.org/10.1371/journal.pone.0185361.
9. Roquer J, Campello AR, Gomis M. Sex differences in first-ever acute stroke. Stroke. 2003 . 34(7), 1581-5, https://doi.org/10.1161/01.STR.0000078562.82918.F6.
10. Gall SL, Donnan G, Dewey HM, Macdonell R, Sturm J, Gilligan A, Srikanth V, Thrift AG. Sex differences in presentation, severity, and management of stroke in a population-based study. Neurology. 2010. 74(12),975-81, https://doi.org/10.1212/WNL.0b013e3181d5a48f.
11. Fonarow GC, Reeves MJ, Smith EE, Saver JL, et al. Age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke. Circulation. 2010. 121(7), 879-91, https://doi.org/10.1161/CIRCULATIONAHA.109.892497.
12. Barrett KM, Brott TG, Brown Jr RD, Frankel MR, Worrall BB, Silliman SL, Case LD, Rich SS, Meschia JF, Ischemic Stroke Genetics Study Group. Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke. Journal of Stroke and Cerebrovascular Diseases. 2007. 16(1), 34-9, https://doi.org/10.1016/j.jstrokecerebrovasdis.2006.11.002.
13. Ton MD, Dao PV, Nguyen DT, Nguyen TH, et al. Sex disparity in stroke outcomes in a multicenter prospective stroke registry in Vietnam. International Journal of Stroke. 2023. 18(9), 1102-11, https://doi.org/10.1177/17474930231177893.