COMPARISON OF SURGICAL TREATMENT OUTCOMES OF MANDIBULAR MOLARS IN ELDERLY PATIENTS WITH AND WITHOUT THE USE OF PLATELET-RICH FIBRIN (PRF) IN BEN TRE PROVINCE IN 2024-2025
Main Article Content
Abstract
Background: Molar tooth extraction is a common dental procedure, yet it can pose significant challenges for older adults due to age-related physiological and pathological factors. In recent years, platelet-rich fibrin (PRF) has gained increasing attention as an adjunct to enhance post-extraction healing. Objectives: To compare the treatment outcomes of mandibular molar extractions performed with or without the application of platelet-rich fibrin in elderly patients at Giong Trom District Medical Center, Ben Tre in 2024-2025. Materials and methods: A controlled clinical intervention study was conducted on 40 elderly patients undergoing surgical extraction of mandibular first and second molars (excluding third molars). Patients were divided into two groups: one receiving PRF application in the extraction socket and the other serving as the control group. Results: Among the 40 evaluated teeth, tooth 36 and tooth 46 accounted for the highest proportions (27.5% each), followed by tooth 37 (25%), while tooth 47 had the lowest frequency (20%). Tworooted teeth represented 72.5% of the sample, and three-rooted teeth accounted for 27.5%. After the first postoperative day, vertical swelling was significantly reduced in the PRF group compared to the control group. Evaluation of soft tissue healing after 7 days, particularly among patients with chronic conditions, revealed a markedly better healing response in the PRF group. The proportion of cases demonstrating good healing was consistently higher in the intervention group compared to the control group. Conclusions: The application of platelet-rich fibrin significantly improves soft tissue healing following molar extractions in elderly patients compared to standard surgical methods without PRF.
Keywords
Molars, PRF, elderly person
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
2. Asoka S,, Panneerselvam E., Pandya A.R., Raja V.B.K., Ravi P. Effect of platelet-rich fibrin on extraction socket healing in diabetic patients - A split-mouth crossover study: A prospective clinical trial. Natl J Maxillofac Surg. 2022. 13(1), 39-43. DOI: 10.4103/njms.njms_422_21.
3. Lam P.C., Ly N.T.B., Ngoc N.T.B. Effect of Platelet-Rich Fibrin (PRF) on pain and swelling after surgical removal of impacted lower third molars. Journal of Health Sciences. 2021. 2(1), 102-109. DOI: 10.32508/stdjhs.v2i1.457.
4. Castro A.B., Van D.J., Temmerman A., Jacobs R., Quirynen M. Effect of different platelet-rich fibrin matrices for ridge preservation in multiple tooth extractions: A split-mouth randomized controlled clinical trial. J Clin Periodontol. 2021. 48(7), 984-995. DOI: 10.1111/jcpe.13463.
5. Phong L.C., Ngoc N.T.B., Ly N.T.B. Đánh giá hiệu quả của sợi huyết giàu tiểu cầu (PRF) lên tình trạng sưng, đau sau phẫu thuật nhổ răng khôn hàm dưới lệch ngầm. Health Sciences. 2021. 2(1), 102-109. DOI: 10.15419/stdjhs.v2i1.457
6. Trybek G., Chruściel-Nogalska M., Machnio M., et al. Surgical extraction of impacted teeth in elderly patients. A retrospective analysis of perioperative complications - the experience of a single institution. Gerodontology. 2016. 33(3), 410-5. DOI: 10.1111/ger.12182.
7. Kantilieraki E., Delantoni A., Angelopoulos C., Beltes P. Evaluation of Root and Root Canal Morphology of Mandibular First and Second Molars in a Greek Population: A CBCT Study. Eur Endod J. 2019. 4(2), 62-68. DOI: 10.14744/eej.2019.19480.
8. Passarelli P.C., Pagnoni S., Piccirillo G.B., et al. Reasons for Tooth Extractions and Related Risk Factors in Adult Patients: A Cohort Study. Int J Environ Res Public Health. 2020. 17(7). DOI: 10.3390/ijerph17072575.
9. Rosette F., Charles B., Essama E.B.L., Bohimbo E., Marie E.N. Coalesce research group international journal of dentistry and oral care what dental extraction tells us about the elderly in Yaoundé: Observational study in cameroon. 2022. 1-5.
10. Mourão C.F.D.A.B., de Mello-Machado R.C., Javid K, Moraschini V. The use of leukocyte-and platelet-rich fibrin in the management of soft tissue healing and pain in post-extraction sockets: A randomized clinical trial. Journal of Cranio-Maxillofacial Surgery. 2020. 48(4), 452-457. DOI: 10.1016/j.jcms.2020.02.020.
11. Zuleika P., Saleh I., Murti K., et al. Platelet-rich Fibrin: A Systematic Review of Its Action", Nature and Science of Medicine. 2024. 7(4), 242-252. DOI: 10.4103/jnsm.jnsm_2_24.
12. Pavlovic V., Ciric M., Jovanovic V., Trandafilovic M., Stojanovic P. Platelet-rich fibrin: Basics of biological actions and protocol modifications. Open Med (Wars). 2021. 16(1), 446-454. DOI: 10.1515/med-2021-0259.