ĐÁNH GIÁ TÍNH HỢP LÝ TRONG SỬ DỤNG THUỐC ĐIỀU TRỊ BỆNH PHỔI TẮC NGHẼN MẠN TÍNH GIAI ĐOẠN ỔN ĐỊNH TRÊN BỆNH NHÂN NGOẠI TRÚ TẠI BỆNH VIỆN ĐA KHOA TỈNH KIÊN GIANG NĂM 2024 – 2025

Abstract

Background: Chronic obstructive pulmonary disease is one of the leading causes of morbidity and mortality worldwide, including in Vietnam, resulting in an increasing socio-economic burden. Recently, early prevention, treatment, and stabilization of COPD have become the main focus to reduce exacerbations and improve patients’ lung function. Objectives: To assess the appropriateness of drug use in treating stable COPD among outpatients. Materials and methods: Cross-sectional study analyzing 400 outpatients diagnosed with and treated for stable COPD at Kien Giang General Hospital from June to October 2024. Results: The male-to-female ratio was 49:1. The mean age was 66.6 ± 9.1 years. The highest percentage of patients had primary education at 46.8%. The duration of COPD averaged 5.5 ± 6.2 years. ICS/LABA was the most used, accounting for 99.8%. The 2-drug combination regimen was used in 64.0%, with the most common being the regimen type (SABA + ICS/LABA) at 32.0%. The rate of rational drug use was only 30.8%, mainly due to non-concordant regimens (69.2%). Education level and regimen type used in treatment of stable COPD were significantly associated with irrational drug use. Conclusion: The rate of rational drug use in stable COPD treatment was low, mainly due to inappropriate regimen selection. Education level and treatment regimen type used were significantly linked to rational drug use.