ĐẶC ĐIỂM SỬ DỤNG, TÁC DỤNG PHỤ TRÊN DA VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN SỬ DỤNG THUỐC BÔI CORTICOSTEROID

Abstract

Background: With the advent of corticosteroids, many dermatological diseases have been effectively treated. However, due to their potent anti-inflammatory effects and rapid symptom relief, these drugs are prone to misuse. Objectives: To describe the epidemiological characteristics, usage patterns, cutaneous adverse effects, and the association between these adverse effects and both the epidemiological characteristics and usage patterns of topical corticosteroids. Material and methods: A cross-sectional descriptive study conducted at Can Tho City Hospital of DermatoVenerology on 67 patients using topical corticosteroids. Results:  Betamethasone dipropionate was the most commonly used active ingredient (34.4%). The majority of topical corticosteroids were combined with other components (32.9%). Physician prescriptions accounted for 56.7% of corticosteroid use. The incidence of adverse effects among patients was 94%, with vasodilation being the most common manifestation (41.8%). There was a significant correlation between the incidence of adverse effects and the frequency of corticosteroid application and between the severity of skin atrophy and the number of components in the topical formulation, with a statistically significant difference (p=0.02). Conclusion: Betamethasone dipropionate was the most commonly used topical corticosteroid. The incidence of adverse effects among corticosteroid users was high, with vasodilation being the most common manifestation. There was a correlation between the incidence of adverse effects and the frequency of corticosteroid application and between the severity of skin atrophy and the number of components in the topical formulation.