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Date Published: 17/12/2022
Online Published: 17/01/2023
Abstract Views: 763
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DOI: https://doi.org/10.58490/ctump.2022i54.379
Issue
No. 54 (2022)
Section
Article
How to Cite
Nguyen , T. M. T. (2023). REVIEW THE ROLE OF THE GUT – MICROBIOTA – BRAIN AXIS IN GASTROINTESTINAL DISORDER AND NEUROPSYCHIATRIC: FROM THEORY TO PRACTICE. Cantho Journal of Medicine and Pharmacy, 54, 202-214. https://doi.org/10.58490/ctump.2022i54.379

REVIEW THE ROLE OF THE GUT – MICROBIOTA – BRAIN AXIS IN GASTROINTESTINAL DISORDER AND NEUROPSYCHIATRIC: FROM THEORY TO PRACTICE

Thi Mong Trinh Nguyen 1,
1 Tra Vinh University

Main Article Content

Abstract

The gut – microbiota – brain axis plays a role in the maintenance of homeostasis, systemic regulation, and inflammation of the nervous system in the body. The gut microbiome and the brain communicate through many pathways by two-way signals: brain-gut and gut-brain, influenced by many factors in the body and environment under many connections. On the other hand, the diversity of the gut microbiota tends to decrease with age. Meanwhile, stress and anxiety significantly affect the brain-gut-microbiome axis at all stages of life. Recently, the gut microbiome has emerged as the key player and keyword in the search for the brain-gutmicrobiome axis. Therefore, the influence between the brain and the microbiome is meaningful with the newly born term "gut-microbiota-brain axis". The review provides current information on the influence of the intestinal microbiome on cerebral behavior and gastrointestinal disorders through the gut-brain axis. At the same time, identify potential therapies to treat gastrointestinal disorders and cerebral dysfunction.

Article Details

Keywords

Gut – brain axis, microbion, stress, gastrointestinal disorder

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