THE VALUE OF COMPUTED TOMOGRAPHY IN DIAGNOSING GANGRENOUS CHOLECYSTITIS IN CAN THO IN 2023 – 2025
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Abstract
Background: Gangrenous cholecystitis is one of the complications of acute cholecystitis. Delayed diagnosis and intervention in cases of gangrenous cholecystitis can lead to gallbladder perforation, sepsis, and septic shock, which pose significant life-threatening risks to patients. Computed tomography plays a crucial role in assessing the condition of the gallbladder and surrounding organs, thereby facilitating accurate diagnosis and management strategies for gangrenous cholecystitis.Objectives: 1. To describe the computed tomography imaging characteristics of acute cholecystitis, 2. To determine the diagnostic value of computed tomography in gangrenous cholecystitis. Materials and methods: A cross-sectional descriptive study was conducted on 40 patients diagnosed with acute cholecystitis who underwent computed tomography imaging prior to surgery within 48 hours, from July 2023 to January 2025. Results: The computed tomography imaging features of acute cholecystitis and gangrenous cholecystitis, showed statistically significant differences in several parameters: gallbladder distention greater than 4cm, decreased mural enhancement, mural striation, intraluminal membranes, pericholecystic stranding, gallbladder perforation and pericholecystic abscess. Gallbladder distention greater than 4cm, decreased mural enhancement, mural striation, intraluminal membranes had sensitivity and specificity of 78.6%, 78.6%, 50%, 42.8%, and 61.5%, 92.3%, 88.5%, 96.2%, respectively. The presence of gas within the gallbladder lumen, gallbladder perforation, and pericholecystic abscess were signs with 100% specificity and positive predictive value in the diagnosis of gangrenous cholecystitis. Conclusions: Computed tomography is a valuable imaging modality with a significant role in the diagnosis of gangrenous cholecystitis.
Keywords
acute cholecytitis, gangrenous cholecystitis, computed tomography
Article Details
References
10.1097/00000658-189401000-00016.
2. Shirah B. H., Shirah H. A., Saleem M. A., Chughtai M. A., Elraghi M. A., et al. Predictive factors for gangrene complication in acute calculous cholecystitis. Ann Hepatobiliary Pancreat Surg. 2019. 23 (3), 228-233, doi: 10.14701/ahbps.2019.23.3.228.
3. Ma Y., Luo M., Guan G., Liu X., Cui X., et al. An explainable predictive machine learning model of gangrenous cholecystitis based on clinical data: a retrospective single center study. World J Emerg Surg. 2025. 20 (1), 1, doi: 10.1186/s13017-024-00571-6.
4. Kim H. Y., Lee J. H., Kim S. G., Lee S.H., Paik S., et al. Ultrasonographic predictors of acute gangrenous cholecystitis in patients treated with laparoscopic cholecystectomy: a single center retrospective study. Scand J Gastroenterol. 2025. 60 (2), 174-183, doi: 10.1080/00365521.2024.2447525.
5. Wu C. H., Chen C. C., Wang C. J., Wong Y. C., Wang L. J., et al. Discrimination of gangrenous from uncomplicated acute cholecystitis: accuracy of CT findings. Abdom Imaging. 2011. 36 (2), 174-178, doi: 10.1007/s00261-010-9612-x.
6. Nguyễn Lê Thảo Nguyên, Nguyễn Thị Phương Loan, Nguyễn Quang Thái Dương. Vai trò của chụp cắt lớp vi tính trong chẩn đoán viêm túi mật hoại tử. Tạp chí Y học Thành phố Hồ Chí Minh. 2022. 26 (2), 159 – 163.
7. Nguyễn Minh Nhật, Huỳnh Quang Huy, Bùi Khắc Vũ , Trần Cảnh Minh, Châu Hoàng Anh. Giá trị của cắt lớp vi tính trong chẩn đoán viêm túi mật cấp không có biến chứng và có biến chứng. Tạp chí Y Dược học Phạm Ngọc Thạch. 2024. 3(4), 188-194, doi: 10.59715/pntjmp.3.4.23.
8. Chang W. C., Sun Y., Wu E. H., Kim S. Y., Wang Z. J., et al. CT Findings for Detecting the Presence of Gangrenous Ischemia in Cholecystitis. AJR Am J Roentgenol. 2016. 207 (2), 302309, doi: 10.2214/AJR.15.15658.
9. Sureka B., Rastogi A., Mukund A., Thapar S., Bhadoria A. S., et al. Gangrenous cholecystitis: Analysis of imaging findings in histopathologically confirmed cases. Indian J Radiol Imaging. 2018. 28 (1), 49-54, doi: 10.4103/ijri.IJRI_421_16.
10. Pushpaketu K. V, N., Badhai S., Mishra A., Sahu S., Debata I., et al. Risk Factors Associated with Gangrenous Cholecystitis: A Cohort Study From Eastern India. Cureus. 2024. 16 (11), e74126, doi: 10.7759/cureus.74126.