Article Sidebar

PDF
Date Published: 25/05/2025
Abstract Views: 239
Views PDF: 87
DOI: 10.58490/ctump.2025i87.3458
Issue
No. 87 (2025)
Section
Article
How to Cite
Le, T. K. D., Nguyen, T. K. N., & Ngo, C. Q. (2025). RELATIONSHIP BETWEEN MOTHERS’ DEMOGRAPHICS AND BLOOD FORMULAS AND SMALL FOR GESTATIONAL AGE NEWBORNS AT CAN THO OBSTETRICS AND GYNECOLOGY HOSPITAL. Cantho Journal of Medicine and Pharmacy, 87, 80-86. https://doi.org/10.58490/ctump.2025i87.3458

RELATIONSHIP BETWEEN MOTHERS' DEMOGRAPHICS AND BLOOD FORMULAS AND SMALL FOR GESTATIONAL AGE NEWBORNS AT CAN THO OBSTETRICS AND GYNECOLOGY HOSPITAL

Thi Kim Duyen Le1, , Thi Kieu Nhi Nguyen1, Chi Quang Ngo1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Small for gestational age (SGA) neonates have a high risk of morbidity, mortality, and poor prognosis. Objectives: 1. To survey mothers' anthropometric indices and blood formula with SGA newborns; 2. To identify related factors between the anthropometric indices and blood formula of mothers and SGA newborns. Materials and Methods: A case-control study was conducted on 80 neonates with small for gestational age newborns (SGA) and 160 neonates with appropriate birth weight for gestational age (AGA). All patients underwent clinical examinations, and data from maternal anthropometric indices and blood formula were collected. Results: The prevalence of SGA neonates delivered by cesarean section (82.5%) and preterm birth (55%) was dominant. Most mothers of SGA neonates were aged >35 years (22.5%), had a pre-pregnancy weight <45 kg (32.5%), height <150 cm (15%), pre-pregnancy BMI <18.5 kg/m² (31.3%), hemoglobin <12 g/dL (32.5%), MCV <80 fL (10%), MCH <28 pg (25%), WBC >10,000/mm³ (56.3%), and platelet count <150,000/mm³ (12.5%). Maternal factors associated with SGA neonates included maternal age at delivery >35 years (OR=4.35; p <0.001), pre-pregnancy BMI <18.5 kg/m² (OR=2.7; p=0.002), pre-pregnancy weight <45 kg (OR=3.79; p <0.001), height <150 cm (OR=5.47; p=0.01), and MCV <80 fL (OR=8.77; p=0.001). Conclusion: The study results indicate that certain maternal anthropometric and hematologic characteristics are associated with an increased risk of delivering small-for-gestational-age (SGA) infants. Advanced maternal age (over 35 years), low pre-pregnancy weight and body mass index (BMI), short stature, and low mean corpuscular volume (MCV) are linked to higher SGA risk. Additionally, preterm birth and cesarean delivery are also associated with an elevated risk of SGA births.

Keywords

Small for gestational age newborns, maternal anthropometric indexes, maternal blood cell counts

Article Details

References

1. Qi Y., Wang X., Mao J. Quantitative assessment of cerebral metabolism and hemodynamics in small-for-gestational-age (SGA) newborns. Quantitative Imaging in Medicine and Surgery. 2021. 11(6), 2321-2332. DOI: https://doi.org/10.21037/qims-20-1040.
2. Hokken-Koelega A.C.S., van der Steen M., Boguszewski M.C.S., Cianfarani S., Dahlgren J. et al. International Consensus Guideline on Small for Gestational Age: Etiology and Management From Infancy to Early Adulthood. Endocrine Reviews. 2023. 44(3). DOI: https://doi.org/539– 565, 10.1210/endrev/bnad002.
3. Wilcox A.J., Cortese M., McConaughey D.R., Moster D., Basso O. The limits of small-forgestational-age as a high-risk category. European Journal of Epidemiology. 2021. 36(10), 985991. DOI: https://doi.org/10.1007/s10654-021-00810-z.
4. Hoàng Thị Hảo, Khổng Thị Ngọc Mai, Nguyễn Bích Hoàng, Nguyễn Văn Cường, Hoàng Thị
Duyên. Một số yếu tố nguy cơ ở trẻ sơ sinh cân nặng thấp tại Bệnh viện Trung ương Thái Nguyên. Tạp chí Y học Việt Nam. 2023. 522(2), 215-219. DOI: https://doi.org/10.51298/vmj.v522i2.4353.
5. Nguyễn Thị Thanh Bình, Mai Thị Thu Hường. Đánh giá chỉ số nhân trắc của trẻ sơ sinh bệnh lý tại Đơn vị Nhi sơ sinh, Bệnh viện Trường Đại học Y - Dược Huế. Tạp chí Y Dược học. 2021. 11(2), 70-76. DOI: https://www.doi.org/10.34071/jmp.2021.2.10.
6. Tian M.Y., Wen S.W., Retnakaran R., Wang H. R., Ma S. J. et al. Novel sex-specific influence of parental factors on small-for-gestational-age newborns. Scientific Reports. 2020. 10(1), 19226. DOI: https://doi.org/10.1038/s41598-020-76196-x.
7. Hoàng Khắc Thường. Nghiên cứu đặc điểm lâm sàng, cận lâm sàng, các yếu tố nguy cơ mẹ - con và kết quả điều trị sơ sinh nhẹ cân tại Khoa Sơ sinh Bệnh viện Phụ sản thành phố Cần Thơ. Trường Đại học Y Dược Cần Thơ. 2021. 131.
8. Desta S.A., Damte A., Hailu T. Maternal factors associated with low birth weight in public hospitals of Mekelle city, Ethiopia: a case-control study. Italian Journal of Pediatrics. 2020. 46, 124. DOI: https://doi.org/10.1186/s13052-020-00890-9.
9. Hoàng Thị Nhật Lệ, Phạm Thị Quỳnh Hoa. Một số yếu tố liên quan đến trẻ sơ sinh cân nặng thấp tại bệnh viện A Thái Nguyên. Tạp chí Y học Cộng đồng. 2025. 66(1), 96-100. DOI: https://doi.org/10.52163/yhc.v66i1.1915.
10. Shah T., Khaskheli M.S., Ansari S., Lakhan H., Shaikh F. et al. Gestational Anemia and its effects on neonatal outcome, in the population of Hyderabad, Sindh, Pakistan. Saudi Journal of Biological Sciences. 2022. 29(1), 83-87. DOI: https://doi.org/10.1016/j.sjbs.2021.08.053.
11. Lâm Thị Kim Ngọc, Phạm Thị Tâm. Nghiên cứu tình hình cân nặng sơ sinh và một số yếu tố liên quan sơ sinh nhẹ cân tại thành phố Trà Vinh năm 2020. Tạp chí Y Dược học Cần Thơ. 2021.
(37), 69-76.