STUDY ON CLINICAL AND SUBCLINICAL CHARACTERISTICS AND ANALYSIS OF TREATMENT OUTCOMES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS WITH PULMONARY TUBERCULOSIS SEQUELAE AT CAN THO CITY TUBERCULOSIS AND LUNG HOSPITAL IN 2024

Hoang Thuy Phuong Tran1, , Thanh Hung Tran1, Thanh Tam Le2, Cong Dang Tran3
1 Can Tho University of Medicine and Pharmacy
2 Can Tho University of Medicine and Pharmacy Hospital
3 Nam Can Tho University

Main Article Content

Abstract

Background: Patients with a history of tuberculosis and chronic obstructive pulmonary disease exhibit specific clinical, subclinical, and therapeutic outcomes that are particularly complex and varied. Objective: To describe the incidence of tuberculosis, chest X-ray characteristics in patients with pulmonary tuberculosis, and some factors related to pulmonary tuberculosis. Materials and methods: A descriptive, prospective cross-sectional study on 30 patients with chronic obstructive pulmonary disease who also had tuberculosis sequelae and another 30 patients who did not at Can Tho City Tuberculosis and Lung Hospital from April 2024 to September 2024. Results: Common symptoms were cough (93.3%), shortness of breath (86.7%), and wheezes and low-pitched wheezes lung sound (95%). The group with tuberculosis sequelae had a significantly higher rate of pulmonary fibrosis with cavitation (p < 0.001), while the group without tuberculosis sequelae more frequently exhibited emphysema on chest X-rays. The median CRP level was higher in the tuberculosis sequelae group (p = 0.008). FVC and FEV1 were significantly reduced in the tuberculosis sequelae group (p < 0.001 and p = 0.001, respectively). The average hospital stay was significantly longer in the tuberculosis sequelae group (15.30 ± 6.48 days vs. 13.93 ± 5.94 days). Conclusion: Patients with chronic obstructive pulmonary disease and tuberculosis should be monitored regularly to reduce the risk of exacerbations and improve their quality of life.

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References

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