OVERVIEW OF ANXIETY LEVELS AND QUALITY OF LIFE IN PATIENTS WITH CHRONIC URTICARIA

Nhu Huynh1, Van Thong Nguyen1, , Thi Hong Cua Trinh1, Thi Thuy Trang Nguyen1, Quang Nhan Tran1, Kim Bich Ly1, Huy Loc Nguyen1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Chronic urticaria is characterized by the presence of wheals, angioedema, or both, persisting for more than six weeks. This condition significantly impacts the quality of life. The prevalence of certain psychiatric disorders, especially anxiety disorders, is considerably higher in patients with chronic urticaria compared to healthy individuals, further decreasing the quality of life. Clinical observations suggest that psychological stress may act as both a trigger and a modulating factor in the progression and treatment response of chronic urticaria. This highlights the potential role of the neuroendocrine system in the pathophysiology of urticaria. A systematic review and meta-analysis indicate that the prevalence of anxiety disorders in patients with chronic urticaria is 30.6%, a substantial figure. Additionally, the degree of impact on the quality of life among these patients ranges from mild to moderate. The GAD-7 is a simple, user-friendly tool with high sensitivity and specificity for anxiety disorder screening. The CU-QOL, recommended by the European Academy of Allergology and Clinical Immunology/ Global Asthma and Allergy European Network/ European Dermatology Forum/ World Allergy Organization (2022), is a questionnaire designed to assess quality of life in chronic urticaria patients. Effectively managing anxiety disorders, alongside traditional urticaria treatments, can improve control and prolong remission, thereby enhancing patients' quality of life. However, there is a notable lack of data regarding the effects of psychiatric interventions on urticaria, including both pharmacological and psychotherapeutic treatments.

Article Details

References

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