STUDY ON THE OPTIMIZATION EXTRACTION OF TOTAL FLAVONOID CONTENT FROM OROXYLUM INDICUM (L.) VENT STEM BARKS
Main Article Content
Abstract
Background: Flavonoid were knonw as a major component of Oroxylum indicum stembarks, which showed many interesting pharmacological activities such as: anti-inflamatory, antibacterial, antioxidant. Objectives: The extract conditions of total flavonoid content from O. indicum stem barks were investigated and optimized. Materials and method: O. indicum stem barks were collected in Hoa Binh in October, 2019. The extract conditions for study including: extraction method, solvent, time, and solid/liquid ratio. The optimization of extraction process was performed using one factor at a time and response surface methodology (RSM). Results: The reflux extraction method was chossed. The RSM results demonstrated that the optimal conditions for total flavonoid content extraction were a solvent extract of ethanol 71%, an extraction time of 46 min, and a solvent to feed ratio of 19 ml/g. The average yield of three times extraction was 90.13%. Conclusion: The investigation and optimization of total flavonoid content extraction process from O. indicum stem barks was completed.
Keywords
Oroxylum indicum, total flavonoid content, one factor at a time, response surface methodology
Article Details
References
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