Peripheral arterial disease is becoming more common worldwide. In Vietnam, its prevalence is rising due to increasing cases of diabetes and high blood pressure. Rheography is a non-invasive method used to diagnose peripheral arterial disease, but it is not widely used in healthcare centers, especially in the Mekong Delta. This study aims to summarize current rheography knowledge and suggest future research directions. Rheography measures changes in electrical resistance (impedance) in body tissues as blood flow changes. This technique, also known as impedance plethysmography, helps assess blood circulation in the limbs. At Can Tho University of Medicine and Pharmacy Hospital, a rheometer with six electrodes is used to measure these changes. The rheography procedure starts with healthcare professionals explaining the procedure to patients, then body measurements are taken, and the electrodes are positioned based on the examined blood vessels. The results appear as waveforms, which help assess vascular tone (the state of blood vessels) and blood flow intensity, which correspond to different phases of the heartbeat. Rheography is useful in diagnosing blood vessel problems such as peripheral arterial disease, deep vein thrombosis, and cardiac autonomic neuropathy. However, the effectiveness of rheography depends on the expertise of the reader. In addition, certain conditions, such as calf thrombi or nonocclusive proximal clots, are harder to diagnose because these conditions only partially block the blood vessels. Future research should focus on the use of rheography in combination with other diagnostic methods and the effectiveness of this combination in disease scanning.