GIÁ TRỊ TẦM SOÁT UNG THƯ CỔ TỬ CUNG BẰNG PHỐI HỢP PHƯƠNG PHÁP CYPREP PAP TEST VÀ XÉT NGHIỆM HPV REALTIME PCR Ở PHỤ NỮ KHÁM PHỤ KHOA TẠI BỆNH VIỆN QUỐC TẾ PHƯƠNG CHÂU NĂM 2021-2022

Abstract

  Background: Cervical cancer is one of the common malignancies among cancers for women. Objectives: Determine the positive rate and value of each method Cyprep Pap test, HPV realtime PCR and combination of both methods (Co-testing) in cervical cancer screening in women. Materials and method: A cross-sectional study of 911 women aged 18-65 years old who attended a gynecological examination at Phuong Chau International Hospital from April 2021 to February 2022. Results: Cyprep Pap test positive rate is 1.32%; the rate of HPV infection detected by Realtime PCR technique is 14.27%; The rate of abnormal results by Co-testing method is 14.49%. The Cyprep Pap test method has a sensitivity of 87.50%; specificity is 95.18%; positive predictive value is 63.63%; negative predictive value is 98.75%. The HPV Realtime PCR test has a sensitivity of 87.50%; specificity is 56.62%; positive predictive value is 16.27%; negative predictive value is 97.91%. The Co-testing method has a sensitivity of 100%; specificity is 55.42%; positive predictive value is 17.78%; The negative predictive value is 100%. Conclusion: Choosing a test for cervical cancer screening by Co-testing will be effective in terms of screening value for patients.