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STUDY ON THE CLINICAL, PARA-CLINICAL CHARACTERISTICS AND SHORT-TERM TREATMENT RESULTS OF HELLP SYNDROME IN WOMAN WITH PRE-ECLAMPSIA HOSPITALIZED AT CANTHO GENERAL CENTRAL HOSPITAL DURING 2020 – 2021
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Abstract
Background: HELLP syndrome is a life-threatening condition with hemolysis, elevated liver enzymes, and low platelets, has historically been classified as a complication of severe Preeclampsia. Although we have many advances for screening and diagnosing Preeclampsia, HELLP syndrome is still a matter of concern in clinical practice. Objectives: Describe clinical and para-clinical characteristics, classification, complications and short-term treatment results of women with HELLP syndrome. Materials and method: Case series report carried out in 15 pregnant women with preeclampsia and HELLP syndrome who have been diagnosed at Can Tho General Central Hospital from 01/12/2020 to 01/12/2021. Results: In 83 pregnant women with preeclampsia admitted to the hospital, there were 15 pregnant women with HELLP syndrome, 60%, 40% patients had HELLP syndrome complete and incomplete. Multiparious was 73%. The most common severe symptom was epigastric pain. The average systolic blood pressure was 149.68±27.63mmHg, and 94.84±16.91mmHg diastolic. 80% pregnant women had a decrease of platelets, 66.7% had elevated liver enzymes. Average proteinuria from 2.48±3.20g/l, liver enzyme, serum LDH concentration had increasing to admitted to hospital and decreasing after pregnancy termination. The most common complication in mothers was blood clotting disorder, accounting for 71.4%. This study also showed rate of neonatal deaths and stillbirth with 25%, 60% of the newborn had APGAR 5 minutes above 8 points. The average hospitalization was 9.14±3.66 days. The good treatment outcomes was 74.2%. The mainly therapy of pregnancy termination was cesarean section. Conclusion: HELLP syndrome is still a dangerous obstetric complication. Pregnant with HELLP syndrome should be terminated pregnancy when diagnosed.
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Keywords
HELLP syndrome, preeclampsia, treatment results of HELLP syndrome, maternity, termination of pregnancy
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