Clinical features and the outcomes evaluation of hypertrophic scar treatment with triamcinolone injection at Can Tho University of Medicine and Pharmacy Hospital

Nguyen Van Lam 1,, Ly Quang Huy1, Vo Thi Hau1, Pham Thanh Thao1, Nguyen Ky Nam1, Ha Thi Thao Mai1
1 Can Tho University of Medicine and Pharmacy

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Abstract

Background: Excessive scarring has both cosmetic and psychological repercussions. Intra- scar injection, for example, makes a significant contribution to enhancing treatment efficiency.


Objectives: To describe the morphological features, categorize, and assessing the effects of Triamcinolone injection therapy of hypertrophic scars. Materials and methods: A cross-sectional descriptive study of 80 patients with hypertrophic scars treated with triamcinolone intralesional injection at Can Tho University of Medicine and Pharmacy Hospital from 5/2018 to 5/2021. Results: There were 80 patients in all, with a male/female ratio of 1/1.05 and a median age of 15-35. There were 129 scars in all, with scar age >1 year accounting for 83%, keloid scars accounting for 64%, and hypertrophic scars accounting for the remaining 36 percent. Scars are most commonly seen on the trunk, accounting for 53.5 percent of all scars, particularly on the anterior chest wall. When the source of scars was discovered, trauma and acne accounted for 24% and 23%, respectively, while the rest were predominantly spontaneous scars, accounting for 49%. Scarring and discomfort of mild to moderate severity were common clinical symptoms; scars larger than 5cm in size had more symptoms than scars smaller than 5cm. Prior to the therapy, the mean Vancouver Score Scale-VSS was 6.55±2.13. After 24 weeks of the therapy, 96.7% of patients had entirely improved itching symptoms, 75% had completely improved pain, and 25% still had minimal pain. After therapy, the mean Vancouver Score Scale-VSS was 2.55±1.81 (p<0.05). At week 24, 3.75% of patients experienced skin shrinkage, 3.75% experienced depigmentation, and 13.75% experienced vasodilation. Conclusion: Triamcinolone intralesional injection should be utilized as a first-line therapy for hypertrophic scarring.

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