KẾT QUẢ ĐIỀU TRỊ ĐỘT QUỴ THIẾU MÁU NÃO CỤC BỘ CẤP CÓ SỬ DỤNG ALTEPLASE TẠI BỆNH VIỆN ĐA KHOA TỈNH SÓC TRĂNG

Abstract

Background: Alteplase improves functional outcomes when administered within 4.5 hours of the onset of acute ischemic stroke (AIS). Objectives: To describe the general characteristics and evaluate the treatment outcomes of patients with AIS who received Alteplase. Materials and methods: Cross-sectional study of 46 patients with AIS who received Alteplase at Soc Trang General Hospital. Results: 63% patients were in the 60-79 age group, time from onset/normal to Alteplase injection was 3.56±1.74 (hour). The average NIHSS score after 24 hours of Alteplase administration decreased by more than 4 points (p< 0.001), 4.3% of patients had cerebral hemorrhage. At 3 months: 56.5% patients with good recovery (mRS from 0 to 1) and 2.2% of patients died (mRS equal to 6). Conclusion: Alteplase therapy within the first 4.5 hours of acute ischemic stroke onset is effective in promoting good neurological recovery.