ĐỐI CHIẾU CÁC TÍP MÔ BỆNH HỌC VỚI MỘT SỐ ĐẶC ĐIỂM GIẢI PHẪU BỆNH TRONG UNG THƯ BIỂU MÔ ĐẠI TRỰC TRÀNG

Abstract

Background: Colorectal cancer is one of the most common cancers in the world. During pathological staging, patients are divided into different prognostic groups based on three factors: the level of invasion of the primary tumor, the number of metastatic lymph nodes and the presence of distant metastatic sites. Objectives: To determine the rate of histological types and compares with some pathologic features of colorectal and rectal carcinoma. Materials and methods: Cross-sectional study describing 156 cases operated on and histopathologically diagnosed as colorectal carcinoma, at Da Nang Oncology Hospital from January 2018 to the end of August 2020. Re-read the specimens, classify the histological type, invasion, lymph node metastasis, and distant metastasis according to the WHO 2010 classification. Results: Adenocarcinoma NOS has the highest rate of 80.1%; T3 invasion accounts for the highest rate of 60.3%. The lymph node metastasis rate is 47.5%; The rate of distant metastasis is 9.0%. Mucinous adenocarcinoma and signet ring cell carcinoma have a higher invasion rate of T3 and T4 than the other types. The mucinous, ring cell, micropapillary and cribriform comedo-types have a high rate of positive lymph nodes. This difference is statistically significant with p < 0.05. In the singlesite metastasis group M1a, micropapillary carcinoma has a higher rate of single-site metastasis than the conventional adenoma type. However, in the M1c peritoneal metastasis group, the ring type predominates at a rate of 33.3% compared to conventional adenocarcinoma with p < 0.05. Conclusion: Conventional breast cancer accounts for the highest rate; T3 invasion has the highest rate. The lymph node metastasis rate is 47.5%; The rate of distant metastasis is 9.0%. There is a relationship between histopathological type and the degree of invasion and lymph node metastasis with p<0.05.