ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN NHẬP VIỆN VÌ ĐỢT CẤP BỆNH PHỔI TẮC NGHẼN MẠN TÍNH CÓ CHỈ ĐỊNH THỞ MÁY XÂM NHẬP TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

Background: Chronic obstructive pulmonary disease (COPD) exacerbation is an important event in the progression of the disease. There is increasing evidence that chronic obstructive pulmonary disease is a complex disease that not only mainly affects the lungs but also the cause of other systemic manifestations. These diseases aggravate the symptoms of the disease, are one of the causes of acute exacerbations, and increase mortality and hospitalization rates of COPD patients. Objectives: To describe some clinical and para-clinical characteristics of patients hospitalized for exacerbation of COPD with indication for invasive ventilation at Thai Nguyen National Hospital. Methods: Descriptive study with cross-sectional design conducted on 66 COPD patients diagnosed with COPD exacerbation and intubated at Thai Nguyen National Hospital from October 2022 to July 2023. Results: 39.4% of patients were in an excited state when admitted to the hospital; 15.2% were in a coma; 90.0% had cough; 75.8% had snoring rales, 72.7% had wheezing rales; 89.4% had respiratory muscle strain; 66.7% classified D according to GOLD; White blood cells are higher than normal; Arterial blood gases showed acute respiratory acidosis with an average pH of 7.26±0.13; with 78.8% increase in PaCO2 and 77.3% decrease in PaO2; Chest X-ray: mainly patients had inflammatory opacities accounting for 43.9%, followed by dirty lung images and pneumothorax images accounting for 16.7%. Conclusion: The study aims to help manage and treat exacerbations in COPD patients with invasive mechanical ventilation at Thai Nguyen National Hospital.