NGHIÊN CỨU TÍNH KHÁNG KHÁNG SINH CỦA STAPHYLOCOCCUS AUREUS TẠI KHÁNH HÒA VÀ THỪA THIÊN HUẾ NĂM 2022-2023

Abstract

Background: Methicillin-resistant S.aureus (MRSA: Methicillin-resistant S. aureus) has been recognized as a bacteria resistant to many common antibiotics, causing concern in the hospital environment. In addition to methicillin resistance, S.aureus is also resistant to many other drugs, so for a short time it was considered a "super bacteria". Currently, there is no research on infections caused by methicillin-resistant S. aureus and antibiotic resistance of Staphylococcus aureus in Khanh Hoa and Thua Thien Hue. Objectives: To survey the antibiotic resistance rate of S. aureus strains in Khanh Hoa and Thua Thien Hue in the period 2022-2023. Subjects and methods: A crosssectional descriptive study was conducted on S. aureus strains isolated in the microbiology departments of the Hue University Hospital and the Khanh Hoa General Hospital from April 2022 to July 2023, using conventional culture methods. Results: Pus samples had the highest prevalence (70% in Khanh Hoa and 89.9% in Thua Thien Hue), followed by sputum samples at 13%, with other samples below 10%. Among the seven commonly used antibiotics in Khanh Hoa, the antibiotic resistance rates of S. aureus at Khanh Hoa General Hospital and Hue University of Hospital were generally equivalent. However, the resistance rate to Doxycycline was lower in Hue, while the resistance rate to Bactrim was higher in Hue; these differences were statistically significant (p<0.05). Conclusion: The antibiotic resistance rates of S. aureus and MRSA varied significantly between hospitals and regions, depending on the level of antibiotic usage and patient conditions.