Article Sidebar

PDF
Date Published: 20/09/2022
Online Published: 20/09/2022
Abstract Views: 223
Views PDF: 133
DOI: https://doi.org/10.58490/ctump.2022i51.310
Issue
No. 51 (2022)
Section
Article
How to Cite
Lam, N. P., & Pham, V. N. (2022). CIRCUMFERENTIAL RESECTION MARGIN AND SHORT - TERM OUTCOMES OF LAPAROSCOPIC SURGERY FOR COLON CANCER. Cantho Journal of Medicine and Pharmacy, 51, 68-75. https://doi.org/10.58490/ctump.2022i51.310

CIRCUMFERENTIAL RESECTION MARGIN AND SHORT - TERM OUTCOMES OF LAPAROSCOPIC SURGERY FOR COLON CANCER

Nhat Phu Lam1,, Van Nang Pham1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

  Background: Colon cancer is a common malignant disease of gastrointestinal tract. Laparoscopic surgery for colon cancer has been achieving promising, results that are equivalent to open surgery, especially in oncological aspect. While the prognostic implications of positive circumferential resection margins (CRM) have been reported for rectal cancer since 2011 in Vietnam, its significance in colon cancer has not been studied. Objectives: To evaluate circumferential resection margin and evaluates the short–term results of laparoscopic colectomy for colon cancer at the Can Tho University of Medicine and Pharmacy Hospital and Can Tho Central General Hospital. Materials and methods: A cross-sectional prospective study was conducted with 56 colon cancer patients from June 2020 to April 2022. Results: Male/Female was 5/3. The average age of the patients was 58.32 ± 11.7 years. Body Mass Index (BMI) means: 21,35 ± 3,15 kg/m2. The mean length of the procedure was 150.4 min. The postoperative complications: 2 cases of anastomotic leakage (3.6%), anastomotic bleeding: 1.8%. Postoperative pathological results: in almost all cases were moderately differentiated adenocarcinoma (82.1%). T4 accounted for 57.1. Median number of harvested lymph nodes: 12.39. CRM positive involvement in 23.2%, factors independently associated: T stage (T4), positive nodes, CEA ≥ 5 ng/mL, tumor size (≥ 5cm) (p<0.05). Conclusions: Laparoscopic surgery for colon cancer is feasible and safe. Rate of positive CRM was 23.2%.

Article Details

Keywords

colon cancer, laparoscopic surgery, circumferential resection margin (CRM)

References

1. Nguyễn Hoàng Bắc, Nguyễn Hữu Thịnh (2007), Phẫu thuật nội soi cắt đại tràng do ung thư: Kinh nghiệm một phẫu thuật viên. Tạp chí Y học Tp Hồ Chí Minh, 11(4), trang 127-131.
2. Nguyễn Lê Gia Kiệt (2019), Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và đánh giá kết quả sớm phẫu thuật nội soi ung thư đại trực tràng tại Bệnh viện Đại học Y Dược Cần Thơ năm 20172019. Luận văn tốt nghiệp Bác sĩ nội trú, Đại học Y Dược Cần Thơ, Cần Thơ.
3. Huỳnh Thanh Long (2018), Nghiên cứu mức độ di căn hạch và đánh giá kết quả điều trị triệt căn ung thư đại tràng bằng phẫu thuật nội soi. Luận án Tiến sĩ Y học, Học viện Quân Y, Hà Nội.
4. Lê Thanh Nhật Minh (2018), Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và đánh giá kết quả phẫu thuật nội soi một vết mổ điều trị ung thư đại tràng tại Bệnh viện Trường Đại học Y Dược Cần Thơ. Luận văn tốt nghiệp Bác sĩ nội trú, Đại học Y Dược Cần Thơ, Cần Thơ.
5. Phạm Văn Năng (2014), Phẫu thuật cắt đại trực tràng nội soi trong điều trị ung thư đại - trực tràng. Y học thực hành, 928 (8), trang 172 – 174.
6. Charlotte L. Deijen, Jeanine E. Vasmel and et al. (2018), Ten-year outcomes of a randomised trial of laparoscopicversus open surgery for colon cancer. Surg Endosc, 31(6), pp.2607–2615.
7. Goffredo, Peige Zhou, Timothy Ginader and et al. (2019), Positive circumferential resection margins following locally advanced colon cancer surgery: Risk factors and survival impact. J Surg Oncol, 121, pp.538–546.
8. Hyuna Sung, Jacques Ferlay, Rebecca L Siegel and et al. (2020), Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin,71(3), pp. 209-249.
9. Jong Min Lee, Taek Chung, Kyung Min Kim and et al. (2020), Significance of Radial Margin in Patients Undergoing Complete Mesocolic Excision for Colon Cancer. Diseases of the colon & rectum, 63(4), pp.488-496.
10. Petersen, K J Baxter, S B Love and et al. (2002), Identification of objective pathological prognostic determinants and models of prognosis in Dukes’ B colon cancer. Gut 2002, 51, pp.65–69.
11. Sarli L., Lusco D. R, Gabriele Regina and et al. (2018), Predicting Conversion to Ope nSurgery in Laparoscopic Left Hemicolectomy. Surgery Laparoscopy Endoscopy & Percutaneous Techniques, 16(4), pp.212 - 216.
12. Scott N, Jamali, C Verbeke and et al. (2007), Retroperitoneal margin involvement by adenocarcinoma of the caecum and ascending colon: what does it mean? Colorectal Dis, 10, pp.289‐293.
13. Shin, Amar, S H Kim and et al. (2014), Complete mesocolic excision with D3 lymph node dissection in laparoscopic colectomy for stages II and III colon cancer: long-term oncologic outcomes in 168 patients. Tech Coloproctol, 18(9), pp.795-803.
14. Standring S (2008), Large intestine, Gray’s Anatomy: The Anatomical basic of clinical practice. Churchill Livingstone -Elsevier, pp.1137-1162.