NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ VAI TRÒ CỦA PROCALCITONIN TRONG ĐỊNH HƯỚNG ĐIỀU TRỊ KHÁNG SINH Ở BỆNH NHÂN VIÊM PHỔI BỆNH VIỆN TẠI BỆNH VIỆN ĐA KHOA TỈNH KIÊN GIANG NĂM 2023-2024

Abstract

Background: Hospital-acquired pneumonia is one of the most common hospital-acquired infections. Procalcitonin is useful for diagnosing and assessing the severity of pneumonia. Objective: 1. To describe clinical and paraclinical characteristics in patients with hospital acquired pneumonia. 2. To evaluate the role of PCT in guiding antibiotic discontinuation in hospital-acquired pneumonia patients. Materials and methods: A cross-sectional descriptive study was conducted of

61 hospital-acquired pneumonia patients. Results: The rate of symptoms of fever, cough, difficulty breathing and increased sputum secretion were 65.6%, 75.4%, 77.0% and 96.7%, respectively.

Lung’s rales with rales, moist rales and other rales were 77.0%, 24.6% and 18.0% respectively. Abnormal white blood cell counts and increased procalcitonin percentage were 80.3%, and 78.7%, respectively. X-ray showed damage to lungs, accounting for 90.2%. The rate of isolation of microbial agents was 70.5%. Among them, Klebsiella pneumoniae bacteria (32.6%), followed by the other (25.6%), Acinetobacter baumannii (21.4%). The treatment success rate was 80.3%. The rate of recurrent pneumonia was 41.0%. Conclusion: Hospital-acquired pneumonia often had common clinical symptoms including cough with sputum difficulty and crackles in the lungs. X-rays help determine the patient's pneumonia, while blood white blood cells and procalcitonin can be affected by previous antibiotic use. Gram-negative bacteria were often the main cause of hospitalacquired pneumonia. The results of PCT often decreased to normal level with highly successful treatment.