STUDY ON ARRHYTHMIA ON 24- HOUR HOLTER MONITORING AND SOME RELATED FACTORS IN PATIENTS WITH HYPERTHYROIDISM SYNDROME
Main Article Content
Abstract
Background: Cardiac arrhythmias are common in patients with hyperthyroidism syndrome and are often interconnected. The accurate diagnosis of these arrhythmias and their associated factors plays a crucial role in treatment and prognosis. Objective: To determine the prevalence and types of cardiac arrhythmias detected by 24-hour Holter monitoring and to investigate associated factors in patients with hyperthyroidism syndrome at Long An General Hospital from 2023 to 2024. Materials and method: A cross-sectional descriptive study was conducted on 57 patients at Long An General Hospital from July 2023 to June 2024. Results: Arrhythmias were present in 89.5% of patients with hyperthyroidism syndrome. These included sinus tachycardia (26.4%), atrial fibrillation (22.8%), atrial tachycardia (22.8%), atrial premature beats (36.8%), and ventricular premature beats (71.9%). The risk of atrial fibrillation increased with higher levels of NT-proBNP, and lower levels of TSH. Conclusion: Arrhythmias are prevalent in the majority of patients with hyperthyroidism syndrome. There is a statistically significant association between TSH, and NTproBNP levels and the occurrence of atrial fibrillation.
Article Details
Keywords
arrhythmia, hyperthyroidism, Holter
References
2. Tudoran C., Tudoran M., Vlad M., Balas M., Ciocarlie T., Parv F. Alterations of heart rate variability and turbulence in female patients with hyperthyroidism of various severities. Niger J Clin Pract. 2019. 22 (10), 1349-1355, DOI: 10.4103/njcp.njcp_61_18.
3. Ross D. S., Burch H. B., Cooper D. S., Greenlee M. C., Laurberg P., Maia A. L., et al. 2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis. Thyroid. 2016. 26 (10), 1343-1421,
DOI: 10.1089/thy.2016.0229.
4. Madhi W., Ezzaouia K., Yazidi M., Oueslati I., Chihaoui M. Prevalence and factors associated with arrythmia in patients with hyperthyroidism. Endocrine Abstracts. Bioscientifica, 2022. DOI: 10.1530/endoabs.81.P758.
5. Olshausen K. v., Bischoff S., Kahaly G., Mohr-Kahaly S., Erbel R., Beyer J., et al. Cardiac arrhythmias and heart rate in hyperthyroidism. The American journal of cardiology. 1989. 63 (13), 930-933, https://doi.org/10.1016/0002-9149(89)90142-2.
6. Werhahn S. M., Becker C., Mende M., Haarmann H., Nolte K., Laufs U., et al. NT‐proBNP as a marker for atrial fibrillation and heart failure in four observational outpatient trials. ESC heart failure. 2022. 9 (1), 100-109, DOI: 10.1002/ehf2.13703.
7. Xing L. Y., Diederichsen S. Z., Højberg S., Krieger D. W., Graff C., Frikke-Schmidt R., et al. Effects of atrial fibrillation screening according to N-terminal pro-B-type natriuretic peptide: A secondary analysis of the randomized LOOP study. Circulation. 2023. 147 (24), 1788-1797, https://doi.org/10.1161/CIRCULATIONAHA.123.064361.