ĐẶC ĐIỂM LÂM SÀNG, GIẢI PHẪU BỆNH UNG THƯ VÚ XÂM NHẬP TÁI PHÁT

Abstract

Background: Currently, about 40% of breast cancer patients have recurrence and most of these cases have high mortality rates. Objective: To describe the clinical and anatomical characteristics of recurrent invasive breast cancer. Materials and methods: Prospective crosssectional descriptive study of medical records and biopsy specimens of 146 female patients with recurrent invasive breast cancer at Can Tho City Oncology Hospital since January June 2023 to March 2024. Results: Most breast cancer patients relapse in the first 5 years after treatment (accounting for 76.7%), especially in the first 3 years. Clinical characteristics: the most common type of recurrence was distant metastasis (73.3%), often metastases to more than 1 organ (57.9%), the most common site of metastasis was bone (29.5%), lung (28.8%), liver (22.6%). Histopathological characteristics: the most common histological type was the NST type (95.9%), the main histological grade was grade 2 (89%), the positive rate of ER and PR in the late recurrence group was higher than in the group with In the early recurrence group, the HER2 positive rate in the early recurrence group was higher than in the late recurrence group with p>0.05. Conclusion: Recurrent invasive breast cancer often occurs in the first 5 years after treatment, especially in the first 3 years. The most common type of recurrence is distant metastasis (mainly in the bones, lungs, and liver). The most common histological type is the non-specific type with mainly grade 2 histology. The ER and PR positive rates are higher in the late recurrence group, and the HER2 rate is higher in the early recurrence group.