SURVEY OF PREVALENCE, EXTENT AND FACTORS RELATED TO HYPONATREMIA IN CIRRHOSIS AND ASCITES PATIENTS
Main Article Content
Abstract
Background: Hyponatremia is common in patients with decompensated cirrhosis and portal hypertension. Hyponatremia is associated with a significant deterioration in quality of life. Objectives: To survey rates, extent and factor of hyponatremia in cirrhosis ascites patients. Materials and method: Prospective cross-sectional descriptive study of 110 patients with cirrhosis ascites hospitalized for treatment at the Department of Internal Medicine Gastroenterology - Hematology - Endocrinology Long An General Hospital during the research period 4/2023 - April 2024. Patients were divided into three groups according to serum sodium concentration as follows: (1) serum sodium < 135 mmol/L, and (2) serum sodium serum > 135 mmol/L. Results: The rate of patients with cirrhosis and ascites with hyponatremia was 71.8%. The rate of patients with hyponatremia < 130 mmol/l requiring treatment was 32.3%. In the group of patients with hyponatremia, most of patients were men, accounting for 90%. The average age was 54.5 years old. Nearly 2/3 of patients had a history of alcoholism and 26.6% of patients had a history of hepatitis B. Most patients with hyponatremia hadclinical fatigue and anorexia. Noting the correlation in clinical status, patients with hyponatremia had increased rates of fatigue and hepatic encephalopathy. No statistically significant association was noted in the groups of patients with hyponatremia and normal blood sodium often in clinical factors: age, gender, history, clinical manifestations and Child-Pugh stage, liver size, serum Albumin index, transaminase index blood NH3. Conclusion: The rate of hyponatremia in patients with cirrhosis ascites is quite high. Attention should be paid to electrolyte testing in patients with cirrhosis ascites to detect and treat hyponatremia.
Keywords
cirrhosis and ascites, hyponatremia, electrolyte disorders
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References
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