Article Sidebar
Views PDF: 413
MICROBIOLOGICAL AGENTS AND RESULTS OF TREATMENT OF RESPIRATORY-DISTRESS PNEUMONIA IN CAN THO CHILDREN’S HOSPITAL
Main Article Content
Abstract
Background: Pneumonia is one of the significant causes of death in children. Respiratory distress is a common complication and leading cause of death in pneumonia. In Can Tho, there are currently no studies on the causative agent of respiratory-distress pneumonia in children. Objective: to determine the rate of microbiological agents, the antibiotic resistance of some isolated bacteria and the results of treatment in children with respiratory-distress pneumonia at Can Tho Children’s Hospital. Materials and methods: Descriptive cross-sectional study. This study was conducted on 102 pediatrics with respiratory-distress pneumonia admitted to the Department of Respiratory, General Internal Medicine, Emergency, Intensive care Unit, Can Tho Children’s Hospital from May 2020 to March 2021. The patient was performed Real-time PCR (Polymerase chain reaction) and bacterial isolate culture of naso tracheal aspiration (NTA) at Nam Khoa Bitotek Laboratory, Ho Chi Minh city. At the same time, children were treated according to the pneumonia treatment protocol of Can Tho Children's Hospital. Results: the positive Real-time PCR rate was 95.1% (including co-infection and single infection) which was higher than the positive NTA culture rate of 70.6% (bacterial single infection), the rate of co-infection was high (80.4%). Among bacterial, Streptococcus pneumoniae pneumoniae accounted for the highest percentage (65.7%). Among viruses, Respratory syncytial virus (RSV) accounts for the highest proportion (25.5%). Regarding treatment, most of children respond to initial antibiotic treatment (76.4%). Conclusion: Streptococcus pneumoniae and RSV are the two most commonly found agents causing respiratorydistress pneumonia in children.
Article Details
Keywords
Respiratory-distress pneumonia, children, microbiological agents
References
2. Cao Phạm Hà Giang, Phạm Thị Minh Hồng (2016), Đặc điểm lâm sàng, cận lâm sàng và điều trị của trẻ viêm phổi nặng do vi khuẩn, do siêu vi và do đồng nhiễm vi khuẩn-siêu vi tại Bệnh viện Nhi Đồng 2, Y học TP Hồ Chí Minh, 20 (1), tr. 63-69.
3. Chung Hữu Nghị (2011), Đặc điểm bệnh nhi tử vong có viêm phổi nhập khoa hô hấp Bệnh viện Nhi đồng 1, Y học TP Hồ Chí Minh, 15 (1), tr. 286-293.
4. Nguyễn Phước Trương Nhật Phương, Phan Hữu Nguyệt Diễm (2008), Nhận xét về kết quả kháng sinh trị liệu trong viêm phổi cộng đồng trẻ em từ 2 - 59 tháng tại khoa Hô Hấp bệnh viện Nhi Đồng 1, Y học thành phố Hồ Chí Minh, 12 (1), tr. 79-87.
5. Bùi Lê Hữu Bích Vân, Phan Hữu Nguyệt Diễm, Phạm Hùng Vân (2016), Tác nhân gây viêm phổi không đáp ứng với điều trị kháng sinh ban đầu ở trẻ dưới 5 tuổi tại khoa Nội tổng quát 2 Bệnh viện Nhi Đồng 1, Y học TP Hồ Chí Minh, 20 (1), tr. 41-48.
6. Gerber J S, Coffin S E, Smathers S A, Zaoutis T E (2009), Trends in the incidence of methicillinresistant Staphylococcus aureus infection in children's hospitals in the United States, Clin Infect Dis, 49 (1), pp. 65-71.
7. Lee K H, Gordon A, Foxman B (2016), The role of respiratory viruses in the etiology of bacterial pneumonia: An ecological perspective, Evol Med Public Health, 2016 (1), pp. 95-109.
8. Robert M. Kliegman MD B. M. D. S. M., Joseph St. Geme MD (2015), Community-Acquired Pneumoniae, Nelson Texbook of Pediatrics, pp. 2088-2094.
9. World Health Organization (2013), Pneumonia, Pocket book of hospital care for children: Guidelines for the management of common illness with limit resources, WHO, Geneva, pp. 76-87.
10. World Heath Organization (2021), Pneumonia, Fact sheets từ: https://wwwwhoint/newsroom/fact-sheets/detail/pneumonia.