SOME CHARACTERS OF ASTHMA IN CHILDREN FROM 6 MONTH TO 5 YEARS WITH INADEQUATE VITAMIN D LEVELS
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Abstract
Background: Asthma in children 6 months to 5 years of age can be related to a number of factors, particularly vitamin D levels. Objectives: Determine the rate of incomplete vitamin D. Investigate some related factors and some clinical and subclinical characteristics, treatment results in asthmatic children aged from 6 months to 5 years with inadequate vitamin D levels. Materials and methods: A cross-sectional approach with analysis of 30 asthma cases from 6 months to 5 years old at the Department of Respiratory Medicine, Can Tho Children's Hospital, from April 1, 2021 to March 1, 2022. Patients classified the severity of the acute asthma attack, were interviewed with available questionnaires, performed blood counts, measured vitamin D level and followed treatments. Results: The average vitamin D concentration in asthma children from 6 months to 5 years was 34.6±11.3ng/ml. The percentage of children with bronchial asthma with inadequate vitamin D was 33.3%. Several factors were associated with inadequate vitamin D levels: children were not exposed to sunlight for 15-30 minutes a day (75.0%), did not take 400UI vitamin D supplements/day (47.4%). In the group of children with bronchial asthma with inadequate vitamin concentrations, the rate of moderate acute attacks accounted for 90.0%, severe attacks accounted for 10.0%, and the rate of relapse in asthmatic children with inadequate vitamin levels (90.0%) higher than in the group with adequate vitamin concentrations (50.0%) with odds ratio of 9.0 (p=0.032). Vitamin D levels and length of hospital stay were negatively correlated (p=0.386). Conclusions: Children with bronchial asthma have inadequate vitamin D levels (33.3%). The rate of moderate-severe exacerbations and relapse rate in children with inadequate vitamin D levels was higher than in the control group.
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Keywords
Asthma,, vitamin D levels
References
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