CLINICAL, SUBCLINICAL CHARACTERISTICS AND ASSOCIATED FACTORS OF ANDROGENETIC ALOPECIA PATIENTS AT CAN THO DERMATO-VENEREOLOGY HOSPITAL IN 2022-2023

Thi Thuy Trang Nguyen1,, Thi Thuy Trang Nguyen1, Van Lam Nguyen1
1 Can Tho University of Medicine and Pharmacy

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Abstract

  Background: Androgenetic alopecia (AGA) is a condition characterized by gradual thinning and shedding of hair, primarily at the frontal and vertex regions, due to genetic predisposition and androgen hormone dependence. It is the most common type of hair loss in both men and women. However, there is limited research on this condition in Vietnam. Some studies have reported an association between clinical disorders and the severity of AGA, such as lipid metabolism disorders, but evidence is scarce. Objectives: To describe the clinical, paraclinical characteristics and some associated factors of androgenetic alopecia patients at Can Tho Dermato-Venereology Hospital in 2022-2023. Materials and methods: A series of cases involving over 30 patients diagnosed with androgenetic alopecia presented for examination at Can Tho Dermato-Venereology Hospital in 2022-2023 were described. Results: The average age of the study population was 40.7±13.7 years, with 60% female and 40% male. Mild AGA accounted for 26.7%, moderate for 40%, and severe for 33.3%. The duration of the disease was 3.3±1.59 years. Positive hair pull test was observed in 73.3% of cases. Family history of AGA was present in 83.3% of cases. The levels of cholesterol were 4.64±0.78 mmol/L, triglycerides 1.51±0.44 mmol/L, HDL-c 1.09±0.26 mmol/L, and LDL-c 2.87±0.51 mmol/L. The severity of the disease was positively correlated with serum cholesterol, triglyceride, and LDL-c levels. There was no difference in HDL-c levels between the severity groups of AGA. Conclusions: The disease typically initiated in middle age. There were differences in severity between genders. The longer the duration of the disease, the more severe it tends to be. Family history was related to the incidence rate of the disease. A positive hair pull test assessed disease activity. There was a correlation between AGA and dyslipidemia.  

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References

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