TỶ LỆ VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN KÉM ĐÁP ỨNG VỚI ĐIỀU TRỊ THIẾU MÁU Ở BỆNH NHÂN BỆNH THẬN MẠN GIAI ĐOẠN CUỐI LỌC MÁU CHU KỲ TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ NĂM 2022-2023

Abstract

Background: Anemia is a common problem in patients with chronic kidney disease especially those undergoing hemodialysis. Treating anemia in this group of patients currently has many difficulties so this study contributes to providing solutions to improve anemia, reduce the need for blood transfusions and improve quality of life for end-stage renal disease patients. Objectives: To evaluate the rate of  poor response to anemia treatment and to find out some related factors in end-stage renal disease patients undergoing hemodialysis. Materials and methods: A crosssectional descriptive study was conducted on 118 end-stage renal disease patients undergoing hemodialysis at Can Tho City General Hospital from October 2022 to October 2023. Results: In 118 patients in the study, the rate of poor response to anemia treatment is 76.3% of which moderate anemia accounted for 40% and severe anemia accounted for 60%. Univariate regression analysis results showed that blood PTH increased >300pg/ml, blood β2M increased >40mg/l, NRL index increased >3.5 were associated with poor response to anemia treatment with p<0.05. Multivariate regression analysis results showed that increased blood β2M >40mg/l was associated with poor response to anemia treatment with p=0.014. Conclusions: End-stage renal disease patients undergoing hemodialysis had a high rate of poor response to anemia treatment (76.3%) and were closely related to blood β2M concentration.