Clinical, sub clinical features of early neurological deterioration during the acute phase with large vessel occlusion and minor neurological deficits

Huynh Quoc Si 1,, Nguyen Thi Hong Tuyen 2, Phan Thi Hong Lac3, Luu Dang Diem Tran3
1 Can Tho Stroke International Services
2 Tra Vinh University
3 . Can Tho Stroke International Services

Main Article Content

Abstract

Background: Patients with mild stroke (NIHSS ≤6) and large vessel occlusion (LVO) generally do not receive revascularization therapy according to stroke guidelines. Several studies have shown that in patients with mild ischemic stroke and LVO, approximately 5% to 40% have early neurological deterioration (END). END was independent predictor of unfavourable outcomes and mortality [1]. Therefore, clinical monitoring of these patients in the acute phase is necessary to have timely interventions when the patient has signs of END. Objective: To describe the clinical and subclinical features of acute ischemic stroke patients with LVO and END. Materials and methods: A cross-sectional descriptive study was conducted on 60 patients at Can Tho Stroke International Services with LVO and END. Results: From March 2021 to December 2021, there were 60 eligible patients. The rate of anterior circulatory stroke was 86.7%. Middle cerebral artery was accounting for 53.3% of culprit lesion. Admission – END interval was 35.1±26.8 hours. END associated with poor neurological deficits (increases NIHSS 6.4 points), functional independence (increases mRS 1.5 points). Conclusion: The clinical and subclinical characteristics of stroke patients with END are similar to the general characteristics of stroke patients.

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References

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