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Date Published: 25/04/2024
Online Published: 25/04/2024
Abstract Views: 32
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DOI: https://doi.org/10.58490/ctump.2024i73.2448
Issue
No. 73 (2024)
Section
Article
How to Cite
Nguyen, T. D., Nguyen, N. M. T., Nguyen, T. P., & Nguyen, D. D. (2024). ANTIMICROBIAL ACTIVITY OF ETHANOL EXTRACT FROM BARK STEM OF Peltophorum pterocarpum (DC.) Backer Ex K. Heyne). Cantho Journal of Medicine and Pharmacy, 73, 180-186. https://doi.org/10.58490/ctump.2024i73.2448

ANTIMICROBIAL ACTIVITY OF ETHANOL EXTRACT FROM BARK STEM OF Peltophorum pterocarpum (DC.) Backer Ex K. Heyne)

Thanh Dung Nguyen1,2,, Ngoc Minh Thu Nguyen3, Thien Phuc Nguyen3, Duc Do Nguyen4
1 Institute of Food and Biotechnology, Can Tho University
2 Nguyen Trung Truc high school
3 Nguyen Trung Truc High School
4 Institute of Food and Biotechnology - Can Tho University

Main Article Content

Abstract

Background: Nowadays, pathogenic bacteria resistant to antibiotics are increasingly common. Many studies show that biologically active compounds derived from plants have good antibacterial properties with multi-mechanism. Objectives: To investigate of antibacterial activity and identification of biologically active compounds from extracts of bark stem of Peltophorum pterocarpum (DC.) Backer ex K. Heyne. Materials and Methods: Investigating the antibacterial ability of Peltophorum pterocarpum (DC.) Backer ex K. Heyne extract by agar diffusion method and identifying biologically active compounds in the extract by GC-MS analysis. Results: The antibacterial ability of ethanol 70% extract in all treatments was better than that of ethanol 90%. The ethanol 70% extract shows antibacterial activity against six species of pathogenic microorganisms such as Escherichia coli, Staphylococcus aureus, Aeromonas hydrophila, Dickeya dadantii, Vibrio parahaemolyticus and Candida albicans with an antibacterial diameter 7.67 mm, 10.0 mm, 12.33 mm, 10.67 mm, 12.67 mm, and 12.0 mm, respectively. The results of identifying compounds in ethanol 70% extract using the GC-MS technique determined the presence of 5 biologically active compounds including 1-phenylpropane-1,2-diol; methyl 4,6-dimethyl-3-nitro salicylate; benzoic acid, methyl ester (CAS) methyl benzoate; phosphonoacetic acid, 3TMS derivative; hexadecanoic acid, methyl ester. Conclusion: Compounds from the extract of the bark stem of Peltophorum pterocarpum (DC.) Backer ex K. Heyne had potential antibacterial activity.  

Article Details

Keywords

Antibacterial, Extract, GC-MS, Peltophorum pterocarpum (DC.) Backer ex K. Heyne

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