NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ PHUN KHÍ DUNG NƯỚC MUỐI ƯU TRƯƠNG 3% TRONG ĐIỀU TRỊ VIÊM TIỂU PHẾ QUẢN CẤP Ở TRẺ EM

Abstract

Background: Nebulised hypertonic saline 3% may improve clinical symptoms and reduce length of hospital stays with acute bronchiolitis, the evidence remains equivocal. Objectives: To describe the characteristics of clinical, laboratory and the therapeutic results of nebuliser hypertonic saline 3% in acute brochiolitis. Materials and methods: Cross-sectional study on pediatric patients diagnosed with acute bronchiolitis from 1 to 24 months with acute bronchiolitis at Can Tho Children’s Hospital, 2022-2024, who using nebulised NaCl 3%. Results: We enrolled 68 children who met the inclusion criteria. Children <6 months accounted for the majority (57.4%) and the male/female ratio was nearly 1.3/1. Wheezing (95.6%) and tachypnea (91.2%) were the main clinical manifestations that cause relatives to take the child to the hospital for examination. Most of the cases had white blood cell counts within normal limits for age (98.5%) and a predominant lymphocyte ratio (95.6%). The average length of hospital stay was 5.79 ± 2,404 days. Clinical Severity score (CSS) and Respiratory Distress Assement Instrument (RDAI) at admission had median 5 (3-9) and 5 (2-10) significantly improvement, respectively, after 3 days of treatment (1(0-4) and 0 (0-3)), with p<0.05. Conclusion: Respiratory rate, CSS, RDAI and length of hospital stay significantly improved after 3 days of nebulised hypertonic saline 3%.