KHẢO SÁT TÌNH HÌNH NHIỄM VÀ KHẢ NĂNG SINH ESBL Ở CÁC CHỦNG VI KHUẨN GRAM ÂM TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2022 - 2023

Abstract

Background: Gram-negative bacteria are among the primary culprits behind primary infections, particularly those acquired in hospital infections. In addition, gram-negative bacteria can also produce ESBL, which is one of the important causes of antibiotic resistance. Objective: To determine the infection rate and ESBL-producing ability of gram-negative bacterial strains at Can Tho University of Medicine and Pharmacy Hospital in 2022-2023. Materials and methods: Crosssectional descriptive study on 187 patients with gram-negative infections and had antibiograms at Can Tho University of Medicine and Pharmacy Hospital from June 2022 to June 2023. Results: The 4 strains of gram-negative bacteria with the highest proportion were Klebsiella spp. (33.2%), Escherichia coli (27.3%), Enterobacter spp. (18.2%) and Citrobacter spp. (16.6%). There were 32.1% of isolated Gram-negative bacteria strains that produced ESBL. The rate of ESBL production in bacteria, Enterobacter spp. is 38.2%, Escherichia coli (37.3%), Citrobacter spp. (35.5%), Klebsiella spp. (22.6%), other strains of gram-negative bacteria (33.3%). Conclusion: Klebsiella spp., Escherichia coli, Enterobacter spp. and Citrobacter spp. has the highest infection rate. The ESBL production rate of gram-negative bacterial strains is 37.3%. Bacteria with high ESBL production rate: Enterobacter spp., Escherichia coli, Citrobacter spp., Klebsiella spp…