TREATMENT OF OVERACTIVE BLADDER WITH MIRABEGRON AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL: A CASE REPORT

Trung Hieu Nguyen1,, Thanh Binh Le1, Vo Tan Phat Quach1, Quoc Cuong Tran1, Quoc Anh Pham1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Overactive bladder is characterised by urinary urgency, usually accompanied by urinary frequency and nocturia, with or without urgency incontinence, in the absence of urinary tract infection or any other obvious pathology. The pathophysiology of overactive bladder is not completely understood but the β3-adrenoceptor, which is highly expressed in the urinary bladder, is thought to be important for mediating human detrusor relaxation during the storage phase. Mirabegron is the first commercially available selective, β3-agonist for the treatment of overactive bladder. Objectives: To evaluate the results of treating overactive bladder with Mirabegron in a clinical case. Materials and methods: We reported a 40-year-old female patient accompanied by urinary frequency and urgency, patient was diagnosed with overactive bladder and treated with mirabegron 50mg/day for 3 months. Results: After 3 months, the patient's symptoms significantly improved, decreased of urination times. Adverse effects were not recorded in patients. Conclusions: A clinical case shows the effectiveness and safety of mirabegron in the treatment of overactive bladder disease.

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References

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