KẾT QUẢ ĐIỀU TRỊ BẰNG TESTOSTERONE THAY THẾ TRÊN BỆNH NHÂN SUY SINH DỤC NAM TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ

Abstract

Background: Male hypogonadism is defined by the European Association of Urology as being associated with reduced testicular function, reduced androgen production, and/or impaired sperm production. Male hypogonadism has many causes and accompanying diseases, such as diabetes, varicocele, etc. Currently, there are many treatment methods such as non-medication, internal medicine, and surgery. Testosterone replacement therapy (TRT) is considered the standard therapy for male hypogonadism, with testosterone gel 1% being a simple and well-tolerated remedy. Therefore, we conducted research on some related factors and the effectiveness of testosterone gel in male hypogonadism. Objectives: To survey some related factors and evaluate the results of treatment with testosterone gel 1% in male hypogonadism at Can Tho University of Medicine and Pharmacy Hospital. Materials and methods: A cross-sectional study was conducted on 61 male patients with symptoms of hypogonadism from 11/2022 to 9/2023. Results: The average age was 65.4 ± 2.3 years. The average total testosterone concentration was 6.7 nmol/L. Testosterone levels were related to factors: level of erectile dysfunction, history of diabetes, body mass index, and degree of varicocele. 100% of patients had increased blood testosterone levels after 3 months of treatment. 19.67% reported side effects when using testosterone gel. Conclusion: Testosterone replacement therapy is considered the standard therapy for male hypogonadism, in which testosterone gel 1% is a simple and welltolerated treatment.