CLINICAL AND PARACLINICAL CHARACTERISTICS AND THE EFFECTIVENESS OF PHOTOTHERAPY IN INDIRECT HYPERBILIRUBINEMIA JAUNDICE CHILDREN AT CAN THO CHILDREN’S HOSPITAL

Thi My Lien Nguyen1,, Nhat Minh Pham, Thi Kim Huong Nguyen1, Thi Kim Han Nguyen1, Quang Nghia Bui1, Quang Khai Tran1
1 Can Tho University of Medicine and Pharmacy

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Abstract

Background: Neonatal jaundice is one of the most common causes of hospitalization during the first week of life in neonates. Phototherapy is a common treatment method, non-invasive. Objectives: 1) To describe the clinical and paraclinical characteristics of pediatric patients with indirect hyperbilirubinemia jaundice at the Neonatal Department, Can Tho Pediatric Hospital. 2) Evaluation of the results of phototherapy as the treatment for indirect hyperbilirubinemia jaundice infants at Can Tho Pediatric Hospital. Materials and methods: Cross-sectional descriptive study on 121 infants with indirect hyperbilirubinemia jaundice and used phototherapy as the treatment at Can Tho Pediatric Hospital from June 2021 to June 2022. Results: Male sex accounted for 50.4%, with a male/female ratio was 1.02, premature infant rate of 17.4%. There were 35.5% of infants with zone 5 jaundice according to Kramer, mainly seen in premature infants. The average indirect bilirubin concentration was 274.4±78.4 µmol/l. Indirect bilirubin was higher in infants born vaginally than those born by surgery, with comorbidities higher than those without comorbidities (p<0.05). Treatment results: 96,7% of neonates were sucessfully cured, 3.3% failed and had to exchange transfusion. Infants with comorbidities, had jaundice in zone 5, were born vaginally, jaundice appeared before 7 age day, prolonged phototherapy exposure time. Conclusion: Treatment of indirect hyperbilirubinemia in neonates with phototherapy was highly effective, need to focus on infants with infection diseases, jaudice appeared soon in order to optimal time treatment and stay hopital.

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References

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