STUDY ON CLINICAL AND SUBCLINICAL FEATURES ON SEVERE AND CRITICAL COVID-19 PATIENTS RECEIVING ADSORBENT DIALYSIS AT CAN THO GENERAL HOSPITAL

Van Lympic Phan1,, Thien Phuoc Duong1
1 Can Tho General Hospital

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Abstract

  Background: The treatment of COVID-19 patients, especially severe and critical ill, remains a challenge for the limited health sector in the current context of our country. Therefore, relying on clinical signs and available tests to assess the severity and possibility of severe progression of the disease is essential to have a timely approach. Objectives: 1). To survey the clinical characteristics of severe and critical COVID-19 patients undergoing adsorbent dialysis; 2). To survey on laboratory characteristics of severe and critical COVID-19 patients undergoing adsorbent dialysis. Materials and methods: A cross-sectional descriptive study on 88 severe and critical COVID-19 patients receiving adsorbent dialysis from 7/2021 to 10/2021 at the ICU COVID19 Department of Can Tho General Hospital. Results: The mean age of the study group was 58.6±11.8. The oldest is 91 years old, the youngest is 24 years old. The male proportion accounted for 39.8%, the female accounted for 60.2%. 100% of patients had dyspnea. Other symptoms: fever accounted for 58%, dry cough accounted for 46%, loss of taste accounted for 34%, loss of sense of smell accounted for 28%. The temperature is 37.3±0.6°C; breathing rate is 27.5±4.6bpm; average blood pressure is 75.9±12.4mmHg; pulse is 102.9±15.4bpm, SpO2 is 92.1±3.5%. Test results: PaO2 75.4±22.9mmHg; PaO2/FiO2 168.7±82.3; CRP 8.7±5.2mg/dl; ferritin 795.6±484.3ng/mL; LDH 395.0±199.7U/L; D-dimer 802,3 (50,0-13189,0)mcg/L; Neutrophil/lymphocyte ratio 11.5±9.2; BUN/creatinine ratio 72.9±60.4; potassium 3.56±0.6mmol/L; AST 63.36±55.1U/L, ALT 60.15±46.8U/L. Conclusion: The most common symptoms in severe and critical COVID-19 patients are dyspnea, fever, and fatigue. All of patients had dyspnea. There is an association between pulse, serum LDH levels with mortality from COVID-19.

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References

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