ĐẶC ĐIỂM LÂM SÀNG, SỰ NẢY CHỒI U VÀ MÔ BỆNH HỌC CỦA UNG THƯ BIỂU MÔ ĐẠI - TRỰC TRÀNG TẠI BỆNH VIỆN UNG BƯỚU CẦN THƠ VÀ BỆNH VIỆN ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2022 - 2023

Abstract

Background: Colorectal cancer is the third most common malignancy and the fourth leading cause of cancer death worldwide. In colorectal cancer, the predominant type is carcinoma. Tumor budding is associated with local tumor recurrence and distant metastasis, reducing the survival time of patients with colorectal carcinoma. Objectives: To describe some related clinical features, tumor budding, histopathological characteristics of colorectal carcinoma. To determine the relationship between tumor budding characteristics and some related clinical and histopathological features of colorectal carcinoma. Materials and methods: A cross-sectional descriptive study on 88 patients diagnosed with colorectal carcinoma at Can Tho Oncology Hospital and Oncology Department - Can Tho University of Medicine and Pharmacy Hospital in 2022-2023. Results: Among the 88 patients, the most common age group was from 60-69, men accounted for the majority (65.9%). The most common tumor locations were in the rectum (36.4%) and the sigmoid colon (34.1%). Adenocarcinoma accounted for the majority (78.4%) and protuberant subtype was the most common (53.4%). Moderately and poorly differentiated accounted for the majority with 73.9% and 23.9% respectively. The density of microscopic invasion to subserosal or surrounding colorectal tissue (pT3) accounted for the highest rate (39.8%). Tumor budding is statistically significantly related to differentiation in colorectal cancer (p<0.001). Conclusions: Adenocarcinoma is usually the highest rate with 78.4%. Most of them were moderately and poorly differentiated, accounting for 73.9% and 23.9%, respectively.