GIÁ TRỊ TIÊN LƯỢNG TỬ VONG CỦA ĐỘ THANH THẢI LACTATE MÁU Ở BỆNH NHÂN SỐC NHIỄM KHUẨN TẠI BỆNH VIỆN ĐA KHOA TỈNH KIÊN GIANG NĂM 2021-2022

Abstract

Background: Septic shock has a mortality rate of 40%-75% in cases of multi-organ failure. Blood lactate concentration is a useful indicator that indirectly reflects the state of perfusion, tissue oxygenation, and oxygen consumption. Objectives: To determine the mortality prognostic value of blood lactate clearance in patients with septic shock. Materials and methods: A prospective, longitudinal desciptives study was used for 33 patients with septic shock at the Intensive Care Unit - Anti-toxicity. The patients were diagnosed with SEPSIS - 3 septic shock in 2016. Results: The mortality rate was 63.6%. The area under the ROC curve of lactate clearance at 6 hours after hospitalization in the mortality prognosis was 0.738 (0.568-0.908); p=0.025. The cut-off point was 17.8%, with a sensitivity of 81.0%, a specificity of 50.0%, a positive predictive value of 73.9%, and a negative predictive value of 60.0%. The area under the ROC curve of lactate clearance at 12 hours after hospitalization in the mortality prognosis was 0.599 (0.406- 0.792); p=0.349. Conclusions: The lactate clearance used at 6 hours after hospitalization was more liable than that at 12 hours after hospitalization.