Article Sidebar

PDF
Date Published: 12/06/2023
Online Published: 12/06/2023
Abstract Views: 151
Views PDF: 84
Issue
No. 27 (2020)
Section
Article
How to Cite
Phan, H. T. N., Pham , V. L., & Luu, T. T. D. (2023). A STUDY OF CHARACTERISTICS, ULTRASONOGRAPHY, SOME RELATED FACTORS AND MEDICAL ABORTION OUTCOME OF UP TO 49 DAYS PREGNANCY WITH UNDER 36 MONTHS CESAREAN SECTION SCAR AT CAN THO GYNECOLOGY OBSTETRICS HOSPITAL. Cantho Journal of Medicine and Pharmacy, 27, 72-79. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/1663

A STUDY OF CHARACTERISTICS, ULTRASONOGRAPHY, SOME RELATED FACTORS AND MEDICAL ABORTION OUTCOME OF UP TO 49 DAYS PREGNANCY WITH UNDER 36 MONTHS CESAREAN SECTION SCAR AT CAN THO GYNECOLOGY OBSTETRICS HOSPITAL

Huu Thuy Nga Phan1,, Van Linh Pham 1, Thi Thanh Dao Luu1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: The incidence of cesarean section is increasing rapidly in Viet Nam, so pregnancy after cesarean section is also increasing. This has led to an increase in the incidence of abortions in women with old cesarean sections and at the same time increased rates of complications and abortion complications. Thus, the method of medical abortion on the uterus with cesarean section scar contributes to reduce the complications of surgical abortion. Objectives: To investigate the efficacy, safety of medical abortion regimen with Mifepristone and Misoprostol in termination of up to 49 days pregnancy and factors related to pregnancy and abortion in women with previous cesarean section. Materials and Methods: Non-control clinical trial in 95 pregnant women with up to 49 days gestation and previous cesarean section at Can Tho Maternity Hospital from April 2016 to July 2017. The regimen used 200mg of Mifepristone and 400μg of Misoprostol 48 hours later, repeated 400μg of Misoprostol in cases of non-vaginal bleeding after 4 hours of administration of Misoprostol. Results: Success rate of the medical abortion with Mifepristone and Misoprostol is 84.2%. Most women had vaginal discharge more than menstruation (41.1%) and lasted more than 14 days (40.0%). Most women have moderate abdominal pain (45.3%). Possible side effects are nausea (6.3%), diarrhea (12.6%), chills or tremor (9.5%). There wasn’t any complication such as uterine rupture, shock of blood loss or infection. Most women have inadequate knowledge of the dangers of abortion (51.6%). In the reasons of this pregnancy, 60% of women fail to use contraception. The most of women admit the reason for the abortion is are enough the number of children. Conclusion: The medical abortion with Mifepristone and Misoprostol is safe and effective in women with previous cesarean section.

Article Details

Keywords

Medical abortion, Mifepristone, Misoprostol, previous cesarean section

References

1. Bộ y tế (2009), “Phá thai bằng thuốc đến hết tuần thứ 9”, Hướng dẫn quốc gia về các dịch vụ chăm sóc sức khỏe sinh sản, 387-389.
2. Lê Thị Giáng Châu (2010), “Hiệu quả của mifepristone và misoprostol trong chấm dứt thai kỳ dưới 49 ngày vô kinh ở phụ nữ có vết mổ cũ lấy thai tại bệnh viện Đa Khoa Sóc
Trăng”, luận văn Thạc sĩ Y học, Đại Học Y Dược TP Hồ Chí Minh.
3. Hồ Ngọc Châu (2015), “Hiệu quả của mifepristone và misoprostol trong phá thai nội khoa
≤ 49 ngày vô kinh tại bệnh viện Đa Khoa tỉnh Bà Rịa – Vũng Tàu”. Luận án Chuyên Khoa cấp II, Đại Học Y Dược TP Hồ Chí Minh.
4. Nguyễn Thị Kiều Loan (2013), “Hiệu quả phá thai nội khoa trong chấm dứt thai kỳ từ 50 đến 63 ngày vô kinh ở phụ nữ có vết mổ cũ lấy thai”. Luận án Chuyên Khoa cấp II, Đại Học Y Dược TP Hồ Chí Minh.
5. Huỳnh Nguyễn Khánh Trang và cs. (2004), “Một số yếu tố liên quan đến nạo phá thai ở phụ nữ có thai lần đầu tại TP. Hồ Chí Minh”, Tạp chí Y tế Công cộng, 2(2), 38-44.
6. Nguyễn Bạch Tuyết, Lê Hồng Cẩm, Trần Thị Lợi (2006), “Hiệu quả, tác dụng phụ của phá thai nội khoa với mifepristone và misoprostol”, Tạp chí Y học TP Hồ Chí Minh, 10(1), 106-110.
7. Hoàng Thị Diễm Tuyết (2008). "Đánh giá hiệu quả phá thai nội khoa ở bệnh nhân có vết mổ lấy thai cũ". Đại học Y dược Thành Phố Hồ Chí Minh Chuyên đề Sản phụ khoa- Hội nghị Việt Pháp, Thành Phố Hồ Chí Minh, 17-23.
8. Beatric A. Chen, Matthew F Reeves (2008), “Misoprostol for treatment of early pregnancy failure in women with previous uterine surgery”, America Journal of Obstetric & Gynecology, 198(6), 626.
9. Elizabeth G. Raymond (2013), “First-trimester medical abortion with mifepristone 200 mg and misoprostol: a systematic review”, Contraception 87:26-37.
10. Gao P., Wang P. (1999), “Clinical observation on termination of early pregnancy of 213 cases after caesarian section with repeated use of mifepristone and misoprostol.”, Reprod Contracept., 10(4):227-33.
11. Gautam R, Agrawal V (2003). "Early medical termination pregnancy with methotrexate and misoprostol in lower segment cesarean section cases". J Obstet Gynaecol Res; 29(4):pp. 251-6.
12. Willmott FJ, Scherf C (2008), “Rupture of uterus in the first trimester during medical termination of pregnancy for exomphalos using Mifepristone/Misoprostol”, BJOG, 115:1575-1577.
13. Wu XQ. et al (2015), “Factors associated with successful transabdominal sonographyguided dilation and curettage for early cesarean scar pregnancy”, Int J Gynaecol Obstet, 131(3), 281-284.
14. Xu J., Chen H., Ma T., Wu X. (2001), “Termination of early pregnancy in the scarred uterus with mifepristone and misoprostol”. Int J Gynaecol Obstet, 72(3), pp. 245-251.