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Date Published: 31/05/2023
Online Published: 31/05/2023
Abstract Views: 494
Views PDF: 290
DOI: https://doi.org/10.58490/ctump.2023i59.1623
Issue
No. 59 (2023)
Section
Article
How to Cite
Nguyen, P. H. T., Nguyen, P. T. T., Vo, L. M. P., & Nguyen, N. Q. (2023). HAIR GROWTH PROMOTING EFFECT OF SHAMPOO CONTAINING CITRUS GRANDIS PEEL ESSENTIAL OIL COMBINED WITH GLEDITSIA SINENSIS ON A SHAVED WHITE MICE MODEL. Cantho Journal of Medicine and Pharmacy, 59, 39-46. https://doi.org/10.58490/ctump.2023i59.1623

HAIR GROWTH PROMOTING EFFECT OF SHAMPOO CONTAINING CITRUS GRANDIS PEEL ESSENTIAL OIL COMBINED WITH GLEDITSIA SINENSIS ON A SHAVED WHITE MICE MODEL

Pham Hong Thanh Nguyen1,, Pham Truc Thanh Nguyen2, Le Mai Phuong Vo2, Ngoc Quynh Nguyen2
1 Can Tho Medical College
2 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Exposure to toxic chemicals, dust, stress, and medical conditions are the causes of hair loss, aesthetic loss, and lack of confidence in communication. A suitable remedy to help improve hair loss is to use a shampoo that stimulates hair growth. Objective: To evaluate the hair growth promoting effect of shampoo containing Citrus grandis peel essential oil combined with Gleditsia sinensis on a shaved white mice model. Material and methods: shampoo containing Citrus grandis peel essential oil combined with Gleditsia sinensis was prepared from grapefruit peel essential oils extracted by steam distillation and Gleditsia sinensis dried powder. The studied mice are 07-week-old male white mice, whose back skin is marked and hair is removed with a specialized hair removal tool. Minoxidil 5% and physiological saline were used as controls. Shampoo, minoxidil and physiological saline are applied once daily on the shaved back skin after bathing with clean water. Results: Research show that the hair in mice using shampoo containing Citrus grandis peel essential oil combined with Gleditsia sinensis began to grow 2.5 days earlier than that in mice without using. Hair length was also significantly increased by 0.328mm (p=0.005) in mice using shampoo. The study team found that using shampoo containing Citrus grandis peel essential oil combined with Gleditsia sinensis increased the number of hairs by 8.25 strands/3.75cm2 (p=0.004). Conclusion: The use of shampoo containing Citrus grandis peel essential oil combined with Gleditsia sinensis on mice shows that shampoo could improve hair condition, helping hair grow faster, more, and longer. 

Article Details

Keywords

Shampoo, Citrus grandis, Hair growth, Gleditsia sinensis

References

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