CLINICAL FEATURES, HISTOPATHOLOGY AND RISK FACTORS IN ORAL CANCER PATIENT'S AT CAN THO ONCOLOGY HOSPITAL IN 2018-2020
Main Article Content
Abstract
Background: Oral cancer (OC) is a frequently occurring and the sixth most common cancer worldwide. Recently, there is no studies about oral cancer in Can Tho city. Objectives: (1) To describe the clinical features, location, stage and risk factors in oral cancer patients; (2). To investigate the histopathology and grading of oral cancer patients. Materials and methods: a crosssectional study was carried out in 102 oral cancer patients at Can Tho Oncology Hospital from May 2018 to February 2020. Results: the average age of the patients was 62.01 ± 12.33, male/female ratio was 2.9/1. The most common site for oral cancer was the tongue, accounts for 40.2%, squamous cell carcinoma was the most common histopathology, accounted for 84,3%, grade 1 and grade 2 were 34.3% and 63.7% respectively. Most patients in stage IV (58.8%). Average time of detection: 7.41 ± 17.65 months. The clinical form of ulceration was 36.3%, invasive ulcers were 34.3%. The main etiological factors were tobacco and alcohol use with 68.6% and 65.7%, respectively. Conclusion: Oral cancer patients in Can Tho Oncology Hospital happened in elderly people, males than females, patients were detected at late period. The main risk factors associated with the development of oral cancer were smoking, consuming alcohol.
Article Details
Keywords
Grade, oral cancer, histopathology, risk factors
References
2. Nguyễn Thị Hồng, Trần Thị Kim Cúc, Nguyễn Thị Phương Thảo (2007), Tình hình ung thư hốc miệng qua các nghiên cứu tại Bệnh viện Ung Bướu Thành phố Hồ Chí Minh, Tạp chí Y học Thành phố Hồ Chí Minh, 11(số 4), tr. 31-36.
3. Trần Thanh Phương (2003), Điều trị phẫu thuật ung thư hốc miệng, Luận án chuyên khoa cấp II, Đại học Y Dược Thành phố Hồ Chí Minh.
4. Nguyễn Trương Thái Trân (2016), Thay đổi chất lượng cuộc sống của bệnh nhân ung thư hốc miệng sau xạ trị 2 tháng, Luận văn thạc sĩ y học, Đại học Y Dược Thành phố Hồ Chí Minh.
5. Kuriakose M. (2017), Contemporary Oral Oncology - Diagnosis and Management, Springer, pp 103 - 184.
6. Omar K., Abdulhameed H., Camile F. (2017), Alcohol and Oral Cancer, pp 61-82.
7. Jehannin K., Dejardin O., Lapotre B. (2017), Oral cancer characteristics in France: Descriptive epidemiology for early detection, J Stomatol Oral Maxillofac Surg, 118(2), pp 84 - 89.
8. Bray F., Ferlay J., Soerjomataram I. (2018), Global cancer statistics 2018 Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J Clin, 68(6), pp 394 - 424.
9. National Comprehensive Cancer Network (2018), NCCN Clinical practice guidelines in Oncology Head and Neck Cancers.
10. Chher T., Hak S., Kallarakkal T.G. (2018), Prevalence of oral cancer, oral potentially malignant disorders and other oral mucosal lesions in Cambodia, Ethn Health, 23(1), pp 1 - 15.
11. Thomson P. (2018), Perspectives on oral squamous cell carcinoma prevention-proliferation, position, progression and prediction, J Oral Pathol Med, 47(9), pp 803 - 807.
12. Max R., Keith H., Michael P. (2018), Oral Pathology, Oxford University Press, pp 64 - 76.
13. Prashanth P. (2019), Oral Cancer Detection, Springer, pp 1-2.
14. Jiang X., Wu J., Wang J. (2019), Tobacco and oral squamous cell carcinoma: A review of carcinogenic pathways, Tob Induc Dis, pp 17 - 29.
15. Le Y. A., Li S., Chen Y. (2019), Tobacco smoking, alcohol drinking, betel quid chewing, and the risk of head and neck cancer in an East Asian population, Head Neck, 41(1), pp 92 - 102.