NGHIÊN CỨU SỰ TUÂN THỦ ĐIỀU TRỊ ARV, YẾU TỐ LIÊN QUAN VÀ ĐÁNH GIÁ KẾT QUẢ CAN THIỆP Ở BỆNH NHÂN HIV TẠI TỈNH BẾN TRE NĂM 2019 – 2020

Abstract

  Background: Adherence to antiretroviral therapy is a very important factor, helping patients prevent the development of HIV virus, limit drug resistance and improve patient health. Objectives: (1) Determine the rate of HIV patients adhering to ARV, (2) Find out some of the factors involved in non-adherence to ARV treatment in HIV patients and (3) Evaluate the intervention results to reduce the non-compliance behavior in outpatient clinic in Ben Tre province from 2019 to 2020. Materials and methods: A cross-sectional descriptive study and community intervention study including before-after evaluation on 290 HIV patients treating ARV at out-patient clinics of Ben Tre province. Results: The proportion of HIV patients adhering to general ARV treatment was 67.2%. Factors related have significant effects on compliance (p<0.05) to non-adherence to ARV treatment in the study include: occupation (worker) (OR=4.76; 95% CI 1.73 – 13.10), distance from home to clinic >30km (OR=2.81; 95% CI 1.56 – 5.04), using of addictive substances (OR=2.56; 95% CI 1.22 – 5.38), no consultation before treatment (OR=2.56; 95% CI 1.04 – 6.33). After the intervention, adherence practice increased from 67.2% to 80.3% (p<0.0001). In which, the compliance rate in on-time re-examination increased from 70.7% to 84.5% (p<0.0001). Conclusions: The proportion of HIV patients who adhere to general ARV treatment is low, accounting for 67.2%. ARV treatment program need to be more focus on treatment adherence counselling; At the same time, it is necessary to speed up the opening of new HIV treatment facilities to facilitate patient travel and reduce the load of provincial hospitals.