ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG, SỰ ĐỀ KHÁNG KHÁNG SINH VÀ KẾT QUẢ ĐIỀU TRỊ VIÊM PHỔI BỆNH VIỆN DO VI KHUẨN ACINETOBACTER BAUMANNII TẠI KHOA HỒI SỨC TÍCH CỰC - CHỐNG ĐỘC BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG CẦN THƠ

Abstract

Background: Increasing antibiotic-resistant caused by Acinetobacter baumannii as been clinically challenging. Treatment failure in hospital acquired pneumonia caused by A.baumannii that took up 54.2% to 89.9% mainly because of Acinetobacter baumannii’s resistance. Objectives: to describe Clinical, subclinical, antibiotic-resistant characteristics and treatment results of hospital acquired pneumonia caused by Acinetobacter baumannii. Materials and methods: 61A.baumannii HAP patients were treated at Intensive Care and Toxic Management Department of Cantho Central General Hospital from 2018-2019 and prospective descriptive cross-sectional study. Results: Early onset HAP was 41%. clinical and subclical characteristics included: 100% fever, 100% respiratory failure. Emperical antibiotics were 62.3% carbapenem, 60.7% quinolone. A. baumanni’sresitance characteristics were: 100% resistant to ticarcillin, ticarcillin/acid clavulanic, cefazolin; 98.4% resistant to imipenem, 97% to meropenem, 98.4% to cefepime, 93.4% to levofloxacin, 95.1% to ciprofloxacin and no case of colistin resistance. 29.5% of the patients got better. Treament failure was 70.5% by either death or unablity to ween from mechanical ventilation. Conclusions: A. baumanniis resistant to many antibiotics except colistin and causes high mortality.