ĐÁNH GIÁ KẾT QUẢ PHÁ THAI NỘI KHOA Ở THAI 9-12 TUẦN BẰNG PHÁC ĐỒ MISOPROSTOL SAU MIFEPRISTONE 24 GIỜ TẠI BỆNH VIỆN ĐA KHOA ĐỒNG THÁP NĂM 2022-2023

Abstract

Background: First trimester abortion can be provide using either medical abortion or surgical techniques. Medical abortion using Mifepristone and Misoprostol can avoid complications associated with surgical priventions. Medical abortion using mifepristone and misoprostol can avoid complication associated with surgical prevention. Medical abortion has been extensively researched worldwide, particularly the use of the Mifepristone-Misoprostol regimen for pregnancies between 9 and 12 weeks gestation. This combined regimen has shown a significantly high success rate ranging from 89% to 97.3%. Shortening the duration of Misoprostol administration after taking Mifepristone offers several advantages, including reducing the waiting time for the expulsion of the pregnancy and alleviating the psychological burden on women undergoing unintended abortions. Objective: To evaluate the outcomes of inpatient medical abortion using the Misoprostol regimen 24 hours after Mifepristone administration, specifically for pregnancies between 9 and 12 weeks gestation. Materials and methods: A case series report was conducted, involving 50 women aged 16 years and above who expressed the desire for inpatient medical abortion at Dong Thap General Hospital from November 2022 to March 2023. Results: The shortened duration of Misoprostol administration after Mifepristone resulted in an effective abortion rate of 88 %. No severe complications were recorded during the study. Less than 10% of the participants experienced minor side effects such as nausea/vomiting, headache, dizziness, and diarrhea. Approximately 95% of the women participating in the study expressed satisfaction with the research method. Conclusion: The Mifepristone-Misoprostol regimen administered 24 hours apart for pregnancies between 9 and 12 weeks gestation demonstrated high efficacy, safety, minimal invasiveness, and high satisfaction levels. Therefore, this method should be considered for routine practice in obstetrics and gynecology hospitals.